Protein Alignment 26-29-p and CTSF

DIOPT Version :9

• Sequence 1: NP_620470.1
• Gene: 26-29-p / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_003784.2
• Gene: CTSF / 8722
• HGNCID: 2531
• Length: 484
• Species: Homo sapiens
• Alignment Length: 470
• Identity: 142/470 - (30%)
• Similarity: 199/470 - (42%)
• Gaps: 99/470 - (21%)

  Fly   124 GTESFLGYTCDKFRLESTIGQKKNIYTLWVRYKKSP-HYPS-SRMPIPVRYEMRGYNTL--LGSH 184
            ||.:.||....:.|   ..|| .::|:|....::.| :.|. .|:|:..:..:..:..|  ||.
Human    57 GTRAVLGLVRGRVR---RAGQ-GSLYSLEATLEEPPCNDPMVCRLPVSKKTLLCSFQVLDELGR- 116

  Fly   185 YDHYYLDYD----------------------------SYEHDDIPNEVFEIDDSLQCVGFPGPGT 221
              |..|..|                            |..|.|..||.|....||
Human   117 --HVLLRKDCGPVDTKVPGAGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISL---------- 169

  Fly   222 GHYATFNPMQEFISGTDEHVDKA--FHHFKRKHGVAYHSDTEHEHRKNIFRQNL---RYIHSKNR 281
               ...:|:.:     |..|..|  |.:|...:...|.|..|...|.::|..|:   :.|.:.:|
Human   170 ---LNEDPLSQ-----DLPVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDR 226

  Fly   282 AKLTYTLAVNHLADKTEEE---------LKARRGYKSSGIYNTGKPFPYDVPKYKDEIPDQYDWR 337
            ....|  .|...:|.||||         |:...|.|.....:.|           |..|.::|||
Human   227 GTAQY--GVTKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSVG-----------DLAPPEWDWR 278

  Fly   338 LYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFR 402
            ..||||.||||.:|||||:|...|::||.:|| |.|.|:.||:|.|:||...  :..|.||....
Human   279 SKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFL-NQGTLLSLSEQELLDCDKM--DKACMGGLPSN 340

  Fly   403 VYQWMLQSGGVPTEEEYGPYLGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLA--LLKHGPLS 465
            .|..:...||:.||::|. |.|....|:.:.......|...|.::.|:.   |||  |.|.||:|
Human   341 AYSAIKNLGGLETEDDYS-YQGHMQSCNFSAEKAKVYINDSVELSQNEQ---KLAAWLAKRGPIS 401

  Fly   466 VAIDASPKTFSFYSHGVY--YEPTCKNDVDGLDHAVLAVGYGSINGEDYWLVKNSWSTYWGNDGY 528
            |||:|.  ...||.||:.  ..|.|...:  :|||||.||||:.:...:|.:||||.|.||..||
Human   402 VAINAF--GMQFYRHGISRPLRPLCSPWL--IDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGY 462

  Fly   529 ILMSAKKNNCGVMTM 543
            ..:......|||.||
Human   463 YYLHRGSGACGVNTM 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	15/57 (26%)
		Peptidase_C1A	331..547	CDD:239068	89/217 (41%)
CTSF	NP_003784.2	Inhibitor_I29	187..243	CDD:214853	15/57 (26%)
		Peptidase_C1	271..482	CDD:278538	89/218 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4265
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.770