Protein Alignment CtsK1 and ctsk

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001072435.1
• Gene: ctsk / 779889
• XenbaseID: XB-GENE-5876967
• Length: 331
• Species: Xenopus tropicalis
• Alignment Length: 321
• Identity: 122/321 - (38%)
• Similarity: 178/321 - (55%)
• Gaps: 19/321 - (5%)

  Fly   238 DEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKN----RAKLTYTLAVNHLADKTE 298
            ||.:|..:..:||.:...|:...:...|:.|:.:|.:.|.:.|    ....||.:|:|||.|.|.
 Frog    21 DETLDAEWDLWKRTYHKQYNGQMDEGLRRLIWEKNFKMITAHNLEYSEGLHTYEMAMNHLGDMTS 85

  Fly   299 EELKARRGYKSSGIY----NTGKPFPYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGT 359
            ||:..    ..:|::    |....|..:....:::|||..|:|..|.|||:::|..|||||:|.:
 Frog    86 EEVVR----TMTGLWVHRRNRSTNFTSEDNTAQEKIPDSIDYRKKGYVTPIRNQGSCGSCWAFSS 146

  Fly   360 IGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLG 424
            :|.|||. ..|..|.||.||.|.|:||  ...|:||.||.....::::..:.|:.:|..| ||:|
 Frog   147 VGALEGQ-LKKKKGKLVDLSPQNLVDC--VKKNDGCGGGYMTNAFEYVRDNKGIDSENAY-PYVG 207

  Fly   425 QDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCK 489
            :|..|..|.....|..|||..|......|.|.|:...||:||.|||...:|.|||.||||:..|
 Frog   208 EDQECMYNATGKAASCKGFKEVQEGSEKALKKAVGLVGPVSVGIDAGLSSFQFYSKGVYYDKDC- 271

  Fly   490 NDVDGLDHAVLAVGYGSINGEDYWLVKNSWSTYWGNDGYILMSAKKNN-CGVMTMPTYVEM 549
             :.:.::|||||||||:.....||:|||||...|||.|||||:.:|:| ||:.::.:|..|
 Frog   272 -NAENINHAVLAVGYGTQKKTKYWIVKNSWGEDWGNKGYILMAREKDNACGISSLASYPVM 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	16/58 (28%)
		Peptidase_C1A	331..547	CDD:239068	95/216 (44%)
ctsk	NP_001072435.1	Inhibitor_I29	28..87	CDD:214853	16/58 (28%)
		Peptidase_C1	117..330	CDD:425470	97/218 (44%)