Protein Alignment CtsK1 and Cts8

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001121688.1
• Gene: Cts8 / 680718
• RGDID: 1588248
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 319
• Identity: 112/319 - (35%)
• Similarity: 166/319 - (52%)
• Gaps: 18/319 - (5%)

  Fly   237 TDEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKN----RAKLTYTLAVNHLADKT 297
            :|..:|..:..:|.|:...|..:.|.:.|. ::.:|::.:...|    :.|..:|:.:|..||.|
  Rat    21 SDPSLDSEWQEWKTKYEKNYSLEEEGQKRA-VWEENMKVVKQHNIEYDQEKKNFTMELNAFADMT 84

  Fly   298 EEELKARRGYKSSGIYNTGKPFPYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGTIGH 362
            .||.  |:...:..:.|..|......|.:: .:|...|||..|.||.||:|..|.|||:|...|.
  Rat    85 GEEF--RKMMTNIPVQNLRKKKSIHQPIFR-YLPKFVDWRRRGYVTSVKNQGTCNSCWAFSVAGA 146

  Fly   363 LEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLGQDG 427
            :||..|.|. |.||.||.|.|:|||...||:||..|......:::..:||:..|..| ||.|::|
  Rat   147 IEGQMFRKT-GRLVSLSPQNLVDCSRPEGNHGCHMGSTLYALKYVWSNGGLEAESTY-PYEGKEG 209

  Fly   428 YCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDV 492
            .|........|.:.||..|..:: .|...|:...||:||.||||..:|.||..|:||||.|.:
  Rat   210 PCRYLPRRSAARVTGFSTVARSE-EALMHAVATIGPISVGIDASHVSFRFYRRGIYYEPRCSS-- 271

  Fly   493 DGLDHAVLAVGYG----SINGEDYWLVKNSWSTYWGNDGYILMSAKKNN-CGVMTMPTY 546
            :.::|:||.||||    ..:|..|||:|||....||.:||:.::...|| ||:.|...|
  Rat   272 NRINHSVLVVGYGYEGRESDGRKYWLIKNSHGVGWGMNGYMKLARGWNNHCGIATYGFY 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	13/58 (22%)
		Peptidase_C1A	331..547	CDD:239068	91/221 (41%)
Cts8	NP_001121688.1	Inhibitor_I29	29..87	CDD:214853	13/58 (22%)
		Peptidase_C1A	115..331	CDD:239068	91/221 (41%)