Protein Alignment CtsK1 and Cts6

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_067420.1
• Gene: Cts6 / 58518
• MGIID: 1889619
• Length: 334
• Species: Mus musculus
• Alignment Length: 346
• Identity: 120/346 - (34%)
• Similarity: 183/346 - (52%)
• Gaps: 31/346 - (8%)

  Fly   210 SLQCVGFPGPGTGHYATFNPMQEFISGTDEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLR 274
            ::.|:|.   |:|..|           .|.:::..:|.:|:::..:|..: |...|:.|:.:|:|
Mouse     8 AILCLGV---GSGALA-----------LDPNLNAEWHDWKKQYEKSYTME-EEGLRRAIWEENMR 57

  Fly   275 YIHSKN----RAKLTYTLAVNHLADKTEEELKARRGYKSSGIYNTGKPFPYDVPKYKDEIPDQYD 335
            .|...|    ..|..:||.:|...|.|.|||  |:...:..|::..|..........|.:|...|
Mouse    58 MIKLHNWENSLGKNNFTLKMNEFGDLTPEEL--RKMMNNFPIWSHKKRKIIRKRAVGDVLPKFVD 120

  Fly   336 WRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGED 400
            ||..|.||.|:.|..|.|||:|...|.:||..| |..|.|..||.|.|:||:...||:||..|:.
Mouse   121 WRKKGYVTRVRRQKFCNSCWAFAVNGAIEGQMF-KKTGKLTPLSVQNLVDCTKTQGNDGCQWGDP 184

  Fly   401 FRVYQWMLQSGGVPTEEEYGPYLGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLS 465
            :..|:::|.:||:..|..| ||.|::|.|..|.....|.|.|||::..:: :....|:...||:|
Mouse   185 YIAYEYVLNNGGLEAEATY-PYEGKEGPCRYNPKNSKAEITGFVSLPESE-DILMEAVATIGPIS 247

  Fly   466 VAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYGS----INGEDYWLVKNSWSTYWGND 526
            .|:|||...||||..|:|::|.|.|:.  ::||||.||||:    .:|..|||:||||...||..
Mouse   248 AAVDASFNRFSFYDGGIYHQPNCSNNT--VNHAVLVVGYGTEGNETDGNKYWLIKNSWGRRWGIG 310

  Fly   527 GYI-LMSAKKNNCGVMTMPTY 546
            ||: ::..:.|:||:.|...|
Mouse   311 GYMKIIRDQNNHCGIATYAHY 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	16/58 (28%)
		Peptidase_C1A	331..547	CDD:239068	91/221 (41%)
Cts6	NP_067420.1	Inhibitor_I29	29..87	CDD:214853	16/58 (28%)
		Peptidase_C1A	116..332	CDD:239068	91/221 (41%)