DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 26-29-p and Ctsr

DIOPT Version :9

Sequence 1:	NP_620470.1	Gene:	26-29-p / 39547	FlyBaseID:	FBgn0250848	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	NP_064680.1	Gene:	Ctsr / 56835	MGIID:	1861723	Length:	334	Species:	Mus musculus

Alignment Length:	322	Identity:	114/322 - (35%)
Similarity:	170/322 - (52%)	Gaps:	25/322 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 DEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKNR----AKLTYTLAVNHLADKTE 298
            |..:|..:..:|.|:..:| |..|.:.::.::.:.|:.|...||    .|..:|:.:|...|:|:
Mouse    22 DSSLDAEWQDWKIKYNKSY-SLKEEKLKRVVWEEKLKMIKLHNRENSLGKNGFTMKMNEFGDQTD 85

  Fly   299 EELKARRGYKSSGIYNTGKPFPYDVPKYKDE----IPDQYDWRLYGAVTPVKDQSVCGSCWSFGT 359
            ||.:......|...:..||..      .|.|    :|...|||..|.||||:.|..|.:||:|..
Mouse    86 EEFRKMMIEISVWTHREGKSI------MKREAGSILPKFVDWRKKGYVTPVRRQGDCDACWAFAV 144

  Fly   360 IGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLG 424
            .|.:| |..:...|.|..||.|.|:|||...|||||.||:.:..:|::|.:||:.:|..| ||.|
Mouse   145 TGAIE-AQAIWQTGKLTPLSVQNLVDCSKPQGNNGCLGGDTYNAFQYVLHNGGLESEATY-PYEG 207

  Fly   425 QDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCK 489
            :||.|..|.....|.|.|||::..:: :....|:...||::..||||.::|..|..|:|:||.|.
Mouse   208 KDGPCRYNPKNSKAEITGFVSLPQSE-DILMAAVATIGPITAGIDASHESFKNYKGGIYHEPNCS 271

  Fly   490 NDVDGLDHAVLAVGYG----SINGEDYWLVKNSWSTYWGNDGYILMSAKKNN-CGVMTMPTY 546
            :|.  :.|.||.||||    ..:|..|||:||||...||..||:.::..||| ||:.:...|
Mouse   272 SDT--VTHGVLVVGYGFKGIETDGNHYWLIKNSWGKRWGIRGYMKLAKDKNNHCGIASYAHY 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	14/58 (24%)
26-29-p	NP_620470.1	Peptidase_C1A	331..547	CDD:239068	91/221 (41%)
Ctsr	NP_064680.1	PTZ00203	15..332	CDD:185513	114/322 (35%)
		Inhibitor_I29	29..87	CDD:214853	14/58 (24%)
		Peptidase_C1A	116..332	CDD:239068	91/221 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830