Protein Alignment CtsK1 and cts12

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: XP_695425.1
• Gene: cts12 / 567046
• ZFINID: ZDB-GENE-050208-336
• Length: 349
• Species: Danio rerio
• Alignment Length: 338
• Identity: 120/338 - (35%)
• Similarity: 168/338 - (49%)
• Gaps: 37/338 - (10%)

  Fly   229 PMQEFISGTDEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKNR----AKLTYTLA 289
            |:| ..|.::|.....::.:|:||.::|..::|..|||.|:..|::.|...|.    ....:.:|
Zfish    26 PVQ-VASESEEEAPTEWNLWKKKHEISYDEESEDVHRKTIWETNMQKIWKNNNDFSFGLSMFKMA 89

  Fly   290 VNHLADKTEEELKARRGYKSSGIYNTGKPFPYDVPKYKDEIPD--------------QYDWRLYG 340
            :|...|.|..|.|...|.|..|..|.           |.:|..              ..|:|..|
Zfish    90 MNKYGDLTSVEYKRLLGSKIKGTGNR-----------KGKITSAQMLRLNAKRLGVTNIDYRAKG 143

  Fly   341 AVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQ 405
            .||.||||..|||||||.|.|.:||..: |:.|.||.||:|.|:|||.:||..||.|......|.
Zfish   144 YVTEVKDQGYCGSCWSFSTTGAIEGQMY-KHTGRLVSLSEQQLVDCSRSYGTYGCSGAWMANAYD 207

  Fly   406 WMLQSGGVPTEEEYGPYLGQDGY-CHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAID 469
            ::: :..:.:.:.| ||...|.. |.......:|.|..:..|.:.:..|...|:...||:|||||
Zfish   208 YVI-NNALESSDTY-PYTSVDTQPCFYEKNLAMAGISDYRFVPAGNEQALADAVATVGPVSVAID 270

  Fly   470 ASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYGSINGEDYWLVKNSWSTYWGNDGYILMSAK 534
            |...:|.|||.|:|.|..|  :.:.|:||||.|||||..|.|||::||||.|.||..||:.|...
Zfish   271 ADNPSFLFYSSGIYKESNC--NPNNLNHAVLVVGYGSEEGTDYWIIKNSWGTGWGEGGYMRMIRN 333

  Fly   535 -KNNCGVMTMPTY 546
             ||.||:.:...|
Zfish   334 GKNTCGIASYALY 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	16/58 (28%)
		Peptidase_C1A	331..547	CDD:239068	92/232 (40%)
cts12	XP_695425.1	Inhibitor_I29	41..101	CDD:462410	16/59 (27%)
		Peptidase_C1A	135..347	CDD:239068	92/217 (42%)