DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 26-29-p and si:dkey-228a15.1

DIOPT Version :9

Sequence 1:	NP_620470.1	Gene:	26-29-p / 39547	FlyBaseID:	FBgn0250848	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	XP_017207744.1	Gene:	si:dkey-228a15.1 / 564472	ZFINID:	ZDB-GENE-060503-344	Length:	313	Species:	Danio rerio

Alignment Length:	289	Identity:	98/289 - (33%)
Similarity:	149/289 - (51%)	Gaps:	15/289 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NP------PKWDPNYIVKGTLYIPYAEIAEPFYAWYDKNTRRSRIDYYGGMVKTYQLAGEGQYGT 79
            ||      |.:...|.|||.:.:|..||.|||.||||....|||||||.|..:|:.:..:..||.
Zfish    25 NPAGNRTVPDFGKMYYVKGVISLPSYEIEEPFEAWYDFEGNRSRIDYYNGTTRTFLIGNDLDYGA 89

  Fly    80 LLKLAPITTKTENNKLTCLQVNGTADQAVDIQSILPDAKPFSLVGTESFLGYTCDKFRLESTIGQ 144
            :.::.|:...::   :.|.|:.||.::.:..||.:||.:.|.....|...|..|:.::..:..|.
Zfish    90 IYQIKPVLPPSD---IKCFQLKGTKEEPIRPQSAMPDVQGFEFEKMEDCKGAQCEVWKTITEAGH 151

  Fly   145 KKNIYTLWVRYKKSPHYPSSRMPIPVRYEMRGYNTLLGSHYDHYYLDYDSYEHDDIPNEVFEIDD 209
            |||.|.|||...:....|::    |.|:||.|:||||.||.|.|.::|..:.....| :||....
Zfish   152 KKNTYRLWVTRPEGNDAPAT----PHRFEMEGFNTLLDSHNDKYSIEYSDFSSQTEP-DVFTPPA 211

  Fly   210 SLQCVGFPGPGTGHYATFNPMQEFISGTD-EHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNL 273
            ...|..||.|...|....||:|:::|... .|..:.|..||.|....|.|:.||:.|:..|.|:.
Zfish   212 GFTCEEFPDPPEQHQILANPIQDYVSTNPVSHAHRMFGPFKEKFNRQYKSEEEHQEREINFVQSF 276

  Fly   274 RYIHSKNRAKLTYTLAVNHLADKTEEELK 302
            |:::|.||..|::|:.:|..||.:..|.:
Zfish   277 RFVNSTNRKGLSFTVGINKRADWSRAETR 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	20/54 (37%)
26-29-p	NP_620470.1	Peptidase_C1A	331..547	CDD:239068
si:dkey-228a15.1	XP_017207744.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581679
Domainoid	1	1.000	194	1.000	Domainoid score	I3120
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.710