Protein Alignment CtsK1 and Cts8

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_062414.3
• Gene: Cts8 / 56094
• MGIID: 1860275
• Length: 333
• Species: Mus musculus
• Alignment Length: 356
• Identity: 115/356 - (32%)
• Similarity: 176/356 - (49%)
• Gaps: 52/356 - (14%)

  Fly   210 SLQCVGFPGPGTGHYATFNPMQEFISGTDEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLR 274
            ::.|:|              :.|....:|..:|..:..:|||....|..:.|.:.|. ::.:|::
Mouse     8 AILCLG--------------VAEVTQSSDPSLDSEWQEWKRKFNKNYSMEEEGQKRA-VWEENMK 57

  Fly   275 YIHSKN----RAKLTYTLAVNHLADKTEEELKARRGYKSSGIYNTGKPFPYDVPKYKDE------ 329
            .:...|    :.|..:|:.||...|.|.||.:...         |..|    ||.::.:
Mouse    58 LVKQHNIEYDQGKKNFTMDVNAFGDMTGEEYRKML---------TDIP----VPNFRKKKSIHQP 109

  Fly   330 ----IPDQYDWRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAY 390
                :|...|||..|.|||||:|..|.|||:|...|.:||..|.|. |.||.||.|.|:|||...
Mouse   110 IAGYLPKFVDWRKRGCVTPVKNQGTCNSCWAFSAAGAIEGQMFRKT-GKLVPLSTQNLVDCSRLE 173

  Fly   391 GNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFK 455
            ||.||..|..|...:::.::.|:..|..| ||.|.||:|..:.....|.|..|..|::::.:..:
Mouse   174 GNFGCFKGSTFLALKYVWKNRGLEAESTY-PYKGTDGHCRYHPERSAARITSFSFVSNSEKDLMR 237

  Fly   456 LALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYG----SINGEDYWLVK 516
             |:...||:||.|||..|:|..|..|:||||.|.:::  ::|:||.||||    ..:|..|||:|
Mouse   238 -AVATIGPISVGIDARHKSFRLYREGIYYEPKCSSNI--INHSVLVVGYGYEGKESDGNKYWLIK 299

  Fly   517 NSWSTYWGNDGYILMSAKKNN-CGVMTMPTY 546
            ||....||.:||:.::..:|| ||:.:...|
Mouse   300 NSHGEQWGMNGYMKLARGRNNHCGIASYAVY 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	14/58 (24%)
		Peptidase_C1A	331..547	CDD:239068	90/221 (41%)
Cts8	NP_062414.3	Inhibitor_I29	29..87	CDD:214853	14/58 (24%)
		Peptidase_C1A	115..331	CDD:239068	90/221 (41%)