Protein Alignment CtsK1 and zgc:110239

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001017633.2
• Gene: zgc:110239 / 550326
• ZFINID: ZDB-GENE-050417-107
• Length: 546
• Species: Danio rerio
• Alignment Length: 549
• Identity: 272/549 - (49%)
• Similarity: 366/549 - (66%)
• Gaps: 17/549 - (3%)

  Fly    10 LAG--LAFSANAT-----NPPKWDPNYIVKGTLYIPYAEIAEPFYAWYDKNTRRSRIDYYGGMVK 67
            |||  |..:|:||     ..|::...|.|||.|.:|||||.|||.||||...:|||||||.|.|.
Zfish     5 LAGFVLLCAADATPVAERTVPEFGKTYHVKGLLSLPYAEIKEPFEAWYDLTGKRSRIDYYHGQVC 69

  Fly    68 TYQLAGEGQYGTLLKLAPITTKTENNKLTCLQVNGTADQAVDIQSILPDAKPFSLVGTESFLGYT 132
            |:.:..:..||.:.|:.|:||:||.|.:.|.|:|||.|:.:..|..|||.:.|.....|.:.|..
Zfish    70 TFFIGNDLDYGAVYKITPVTTETEFNTMKCFQLNGTKDEPIIPQIALPDVQGFEFEKIEYYAGVL 134

  Fly   133 CDKFRLESTIGQKKNIYTLWVRYKKSPHYPSSRMPIPVRYEMRGYNTLLGSHYDHYYLDYDSYEH 197
            |:.::..:|:|.|||.|.|||  .:.....||.|  |..|||.|:|||||||||.|.:||..:..
Zfish   135 CEVWKNVTTVGHKKNTYRLWV--TRPEGIDSSAM--PHHYEMMGFNTLLGSHYDKYIVDYSDFSS 195

  Fly   198 DDIPNEVFEIDDSLQCVGFPGPGTGHYATFNPMQEFISGTD-EHVDKAFHHFKRKHGVAYHSDTE 261
            ...|| :|::...:.|.||||||..|:...||:|:|:..:. .|..:.|.|:|.|....|.::.|
Zfish   196 QVDPN-IFKLPGGMSCGGFPGPGVEHHLLANPIQDFVETSPVSHAHRMFGHYKEKFNRQYDNEME 259

  Fly   262 HEHRKNIFRQNLRYIHSKNRAKLTYTLAVNHLADKTEEELKARRG-YKSSGIYNTGKPFPYDVPK 325
            ||.|::.|..|:||:||.|||.|:::|:||||||::::||...|| .::..::...:|||.::..
Zfish   260 HEEREHNFVHNIRYVHSMNRAGLSFSLSVNHLADRSQKELSMMRGCQRTHKVHRKAQPFPSEIRS 324

  Fly   326 YKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAY 390
            .  ..|:..||||||||||||||:||||||||.|.|.||||.|||. |.|..||||.|:||:|.:
Zfish   325 I--ATPNSVDWRLYGAVTPVKDQAVCGSCWSFATTGTLEGALFLKT-GQLTSLSQQMLVDCTWGF 386

  Fly   391 GNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFK 455
            |||||||||::|.::|:::.||:.|.|.||.|:|.:|.||.:..::||.:.|:.||||.|..|.|
Zfish   387 GNNGCDGGEEWRAFEWIMKHGGISTAESYGAYMGMNGLCHYDKTSMVAQLTGYTNVTSGDILALK 451

  Fly   456 LALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYGSINGEDYWLVKNSWS 520
            .|:.|.||::|:|||:.::|:|||:||||||.|||.::.|||||||||||.:|.|.|||||||||
Zfish   452 AAIFKFGPVAVSIDAAHRSFAFYSNGVYYEPECKNGINDLDHAVLAVGYGIMNNESYWLVKNSWS 516

  Fly   521 TYWGNDGYILMSAKKNNCGVMTMPTYVEM 549
            :|||||||||||.|.|||||.|...|..:
Zfish   517 SYWGNDGYILMSMKDNNCGVATDAIYATL 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	26/54 (48%)
		Peptidase_C1A	331..547	CDD:239068	135/215 (63%)
zgc:110239	NP_001017633.2	Inhibitor_I29	243..298	CDD:214853	26/54 (48%)
		Peptidase_C1A	328..543	CDD:239068	135/215 (63%)