Protein Alignment CtsK1 and Ctss

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: XP_063138486.1
• Gene: Ctss / 50654
• RGDID: 621513
• Length: 342
• Species: Rattus norvegicus
• Alignment Length: 323
• Identity: 123/323 - (38%)
• Similarity: 174/323 - (53%)
• Gaps: 35/323 - (10%)

  Fly   246 HH---FKRKHGVAYHSDTEHEHRKNIFRQNLRYI------HSKNRAKLTYTLAVNHLADKTEEE- 300
            ||   :|:.|...|....|.:.|:.|:.:||::|      ||....  :|::.:||:.|.|.||
  Rat    36 HHWDLWKKTHEKEYKDQNEEDVRRLIWEKNLKFIMLHNLEHSMGMH--SYSVGMNHMGDMTPEEV 98

  Fly   301 ------LKARRGYKSSGIYNTGKPFPYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGT 359
                  |:..|.:..||...:..         ...:||..|||..|.||.||.|..|||||:|..
  Rat    99 IGYMGSLRIPRHWNRSGTLKSSS---------NQTLPDSVDWREKGCVTNVKYQGSCGSCWAFSA 154

  Fly   360 IGHLEGAFFLKNGGNLVRLSQQALIDCSW--AYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPY 422
            :|.|||...||. |.||.||.|.|:|||.  .|||.||.||.....:|:::.:||:.:|..| ||
  Rat   155 VGALEGQLKLKT-GKLVSLSAQNLVDCSTEEKYGNKGCGGGFMTEAFQYIIDNGGIDSEASY-PY 217

  Fly   423 LGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEPT 487
            ...|..||.:.....|....::.:...|..|.|.|:...||:||.||||..:|..|..|||.:|:
  Rat   218 KAMDEKCHYDPKNRAATCSRYIELPFGDEEALKEAVATKGPVSVGIDASHSSFFLYQSGVYDDPS 282

  Fly   488 CKNDVDGLDHAVLAVGYGSINGEDYWLVKNSWSTYWGNDGYILMSA-KKNNCGVMTMPTYVEM 549
            |..:|   :|.||.||||:::|:|||||||||..::|:.|||.|:. .||:||:.:..:|.|:
  Rat   283 CTENV---NHGVLVVGYGTLDGKDYWLVKNSWGLHFGDQGYIRMARNNKNHCGIASYCSYPEI 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	18/62 (29%)
		Peptidase_C1A	331..547	CDD:239068	97/218 (44%)
Ctss	XP_063138486.1	None