DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 26-29-p and ctsz

DIOPT Version :9

Sequence 1:	NP_620470.1	Gene:	26-29-p / 39547	FlyBaseID:	FBgn0250848	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	NP_001006043.1	Gene:	ctsz / 450022	ZFINID:	ZDB-GENE-041010-139	Length:	301	Species:	Danio rerio

Alignment Length:	254	Identity:	75/254 - (29%)
Similarity:	113/254 - (44%)	Gaps:	45/254 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 TGKPFPYDVPKYKDEIPDQYDWR-LYGA--VTPVKDQSV---CGSCWSFGTIGHLEGAFFLKN-- 371
            || |.||:....| |:|.::||| :.|.  |:..::|.:   |||||:.|:...|.....:|.
Zfish    41 TG-PRPYESMNLK-ELPKEWDWRNIKGVNYVSTTRNQHIPQYCGSCWAHGSTSALADRINIKRKA 103

  Fly   372 GGNLVRLSQQALIDCSWAYGNNG-CDGGEDFRVYQWMLQSGGVPTEEEYGPYLGQDGYCHVNNVT 435
            ......||.|.:|||    |:.| |.||:...|::: ..:.|:| :|....|..:|..|...|..
Zfish   104 AWPSAYLSVQNVIDC----GDAGSCSGGDHSGVWEY-AHNKGIP-DETCNNYQAKDQDCKPFNQC 162

  Fly   436 LVAPIKGFVNVTSN-------------DPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVY---- 483
            ......|..|:..|             ..:..|..:...||:|..|.|:.| ...|:.|:|
Zfish   163 GTCTTFGVCNIVKNFTLWKVGDYGSASGLDKMKAEIYSGGPISCGIMATDK-LDAYTGGLYSEYV 226

  Fly   484 YEPTCKNDVDGLDHAVLAVGYG-SINGEDYWLVKNSWSTYWGNDGY--ILMSAKKNNCG 539
            .||.       ::|.|...|:| ..||.::|:|:|||...||..|:  |:.||.|...|
Zfish   227 QEPY-------INHIVSVAGWGVDENGVEFWVVRNSWGEPWGEKGWLRIVTSAYKGGSG 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853
26-29-p	NP_620470.1	Peptidase_C1A	331..547	CDD:239068	68/238 (29%)
ctsz	NP_001006043.1	Peptidase_C1A_CathepsinX	54..295	CDD:239149	68/239 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820