Protein Alignment CtsK1 and CtsK2

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Alignment Length: 345
• Identity: 109/345 - (31%)
• Similarity: 154/345 - (44%)
• Gaps: 41/345 - (11%)

  Fly   222 GHYATFNPMQEFISGTDEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKNRAKL-- 284
            |:.|...|....:|...:     |..|..:.|..|.|..:....:..|......:.:.|.|..
  Fly    94 GNIAKAVPKVPLLSNVQD-----FGDFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQG 153

  Fly   285 --TYTLAVNHLADKTEEEL-------------KARRGYKSSGIYNTGKPFPYDVPKYKDEIPDQY 334
              |:..|||..||.|..|.             |||.......:....||           |||.:
  Fly   154 VHTFKQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLVNLPAKP-----------IPDAF 207

  Fly   335 DWRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWA--YGNNGCDG 397
            |||.:|.|||||.|..|||||:|.|.|.:||..|.|. |:|..||:|.|:||...  :|.|||||
  Fly   208 DWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKT-GSLPNLSEQNLVDCGPVEDFGLNGCDG 271

  Fly   398 GEDFRVYQWMLQ-SGGVPTEEEYGPYLGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKH 461
            |.....:.::.: ..||..|..| ||:...|.|..:.....|.::||..:...|....|..:...
  Fly   272 GFQEAAFCFIDEVQKGVSQEGAY-PYIDNKGTCKYDGSKSGATLQGFAAIPPKDEEQLKKVVATL 335

  Fly   462 GPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYGSINGEDYWLVKNSWSTYWGND 526
            ||::.:::.. :|...|:.|:|.:..|.....  :|::|.|||||..|:|||:|||||...||..
  Fly   336 GPVACSVNGL-ETLKNYAGGIYNDDECNKGEP--NHSILVVGYGSEKGQDYWIVKNSWDDTWGEK 397

  Fly   527 GYILMSAKKNNCGVMTMPTY 546
            ||..:...||.|.:....:|
  Fly   398 GYFRLPRGKNYCFIAEECSY 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	15/58 (26%)
		Peptidase_C1A	331..547	CDD:239068	83/219 (38%)
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	15/59 (25%)
		Peptidase_C1A	204..418	CDD:239068	83/219 (38%)