DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 26-29-p and ctsla

DIOPT Version :9

Sequence 1:	NP_620470.1	Gene:	26-29-p / 39547	FlyBaseID:	FBgn0250848	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	XP_005165325.1	Gene:	ctsla / 321453	ZFINID:	ZDB-GENE-030131-106	Length:	363	Species:	Danio rerio

Alignment Length:	355	Identity:	139/355 - (39%)
Similarity:	193/355 - (54%)	Gaps:	38/355 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 PGTGHYATFNPMQEFISG-------------TDEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFR 270
            ||.|....| .|:.|::.             .|:.::..:..:|:.|...||: ||...|:.|:.
Zfish    17 PGFGTTRVF-IMRVFLAAFTLCLSAVFAAPTLDQQLNDHWDQWKKWHSKKYHA-TEEGWRRIIWE 79

  Fly   271 QNLRYIHSKNRAKL----TYTLAVNHLADKTEEELK-ARRGYKSSGIYNTGKPFP---YDVPKYK 327
            :||:.|...|....    ||.|.:||..|.|.||.: ...|:|    :...:.|.   :..|.:
Zfish    80 KNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFK----HKKDRRFRGSLFMEPNF- 139

  Fly   328 DEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGN 392
            .|:|::.|||..|.|||||||..|||||:|.|.|.|||..|.|. |.||.||:|.|:|||...||
Zfish   140 IEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKT-GKLVSLSEQNLVDCSRPEGN 203

  Fly   393 NGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLGQDGY-CHVNNVTLVAPIKGFVNVTSNDPNAFKL 456
            .||:||...:.:|::....|:.:||.| ||||.|.. ||.:.....|...|||::.|....|...
Zfish   204 EGCNGGLMDQAFQYVKDQNGLDSEESY-PYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMK 267

  Fly   457 ALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYG----SINGEDYWLVKN 517
            |:...||:||||||..::|.||..|:|||..|.:  :.|||.|||||||    .::|:.||:|||
Zfish   268 AIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSS--EELDHGVLAVGYGFEGEDVDGKKYWIVKN 330

  Fly   518 SWSTYWGNDGYILMSA-KKNNCGVMTMPTY 546
            |||..||:.|||.|:. :.|:||:.|..:|
Zfish   331 SWSENWGDKGYIYMAKDRHNHCGIATAASY 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	19/58 (33%)
26-29-p	NP_620470.1	Peptidase_C1A	331..547	CDD:239068	106/222 (48%)
ctsla	XP_005165325.1	Inhibitor_I29	55..113	CDD:214853	19/58 (33%)
ctsla	XP_005165325.1	Peptidase_C1	142..362	CDD:278538	106/223 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.930