Protein Alignment CtsK1 and ctslb

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_571273.2
• Gene: ctslb / 30443
• ZFINID: ZDB-GENE-980526-285
• Length: 352
• Species: Danio rerio
• Alignment Length: 356
• Identity: 143/356 - (40%)
• Similarity: 193/356 - (54%)
• Gaps: 29/356 - (8%)

  Fly   211 LQCVGF---PGPGTGHYATFNPMQEFISGT------DEHVDKAFHHFKRKHGVAYHSDTEHEHRK 266
            ||.|.|   ..||...:|....:  :||..      |..:|..::.:|.:||.:||.|.| ..|:
Zfish     3 LQSVRFACESPPGRMMFALLVTL--YISAVFAAPSIDIQLDDHWNSWKSQHGKSYHEDVE-VGRR 64

  Fly   267 NIFRQNLRYIHSKN----RAKLTYTLAVNHLADKTEEELK-ARRGYKSSGIYNTGKPFPYDVPKY 326
            .|:.:|||.|...|    ....|:.:.:|...|.|.||.: |..||.......:..|. :..|.:
Zfish    65 MIWEENLRKIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYTHDPNQTSQGPL-FMEPSF 128

  Fly   327 KDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAYG 391
             ...|.|.|||..|.|||||||..|||||||.:.|.|||..|.|. |.|:.:|:|.|:|||...|
Zfish   129 -FAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKT-GKLISMSEQNLVDCSRPQG 191

  Fly   392 NNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLGQDGY-CHVNNVTLVAPIKGFVNVTSNDPNAFK 455
            |.||:||...:.:|::.::.|:.:|:.| |||.:|.. |..:....||.|.|||::.|.:..|..
Zfish   192 NQGCNGGLMDQAFQYVKENKGLDSEQSY-PYLARDDLPCRYDPRFNVAKITGFVDIPSGNELALM 255

  Fly   456 LALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYG----SINGEDYWLVK 516
            .|:...||:|||||||.::..||..|:|||..|.:  ..||||||.||||    .:.|..||:||
Zfish   256 NAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSS--SRLDHAVLVVGYGYQGADVAGNRYWIVK 318

  Fly   517 NSWSTYWGNDGYILMSAKKNN-CGVMTMPTY 546
            ||||..||:.|||.|:..||| |||.|..:|
Zfish   319 NSWSDKWGDKGYIYMAKDKNNHCGVATKASY 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	18/58 (31%)
		Peptidase_C1A	331..547	CDD:239068	107/222 (48%)
ctslb	NP_571273.2	Inhibitor_I29	44..102	CDD:214853	18/58 (31%)
		Peptidase_C1	131..351	CDD:425470	107/223 (48%)