Protein Alignment CtsK1 and Ctsk

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_113748.1
• Gene: Ctsk / 29175
• RGDID: 61810
• Length: 329
• Species: Rattus norvegicus
• Alignment Length: 335
• Identity: 130/335 - (38%)
• Similarity: 189/335 - (56%)
• Gaps: 29/335 - (8%)

  Fly   229 PMQEFISGTDEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKN-RAKL---TYTLA 289
            |:..|....:|.:|..:..:|:.||..|:|..:...|:.|:.:||:.|...| .|.|   ||.||
  Rat    10 PVVSFALSPEETLDTQWELWKKTHGKQYNSKVDEISRRLIWEKNLKKISVHNLEASLGAHTYELA 74

  Fly   290 VNHLADKTEEELKAR---------RGYKSSGIYNTGKPFPYDVPKYKDEIPDQYDWRLYGAVTPV 345
            :|||.|.|.||:..:         |.:.:..:|         .|:::..:||..|:|..|.||||
  Rat    75 MNHLGDMTSEEVVQKMTGLRVPPSRSFSNDTLY---------TPEWEGRVPDSIDYRKKGYVTPV 130

  Fly   346 KDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQS 410
            |:|..|||||:|.:.|.|||. ..|..|.|:.||.|.|:||  ...|.||.||.....:|::.|:
  Rat   131 KNQGQCGSCWAFSSAGALEGQ-LKKKTGKLLALSPQNLVDC--VSENYGCGGGYMTTAFQYVQQN 192

  Fly   411 GGVPTEEEYGPYLGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTF 475
            ||:.:|:.| ||:|||..|..|.....|..:|:..:...:..|.|.|:.:.||:||:||||..:|
  Rat   193 GGIDSEDAY-PYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPVSVSIDASLTSF 256

  Fly   476 SFYSHGVYYEPTCKNDVDGLDHAVLAVGYGSINGEDYWLVKNSWSTYWGNDGYILMSAKKNN-CG 539
            .|||.||||:..|  |.|.::||||.||||:..|..||::||||...|||.||:|::..||| ||
  Rat   257 QFYSRGVYYDENC--DRDNVNHAVLVVGYGTQKGNKYWIIKNSWGESWGNKGYVLLARNKNNACG 319

  Fly   540 VMTMPTYVEM 549
            :..:.::.:|
  Rat   320 ITNLASFPKM 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	22/58 (38%)
		Peptidase_C1A	331..547	CDD:239068	98/216 (45%)
Ctsk	NP_113748.1	Inhibitor_I29	26..85	CDD:214853	22/58 (38%)
		Peptidase_C1	115..327	CDD:425470	98/217 (45%)