Protein Alignment CtsK1 and Cts7l2

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: XP_225137.5
• Gene: Cts7l2 / 290981
• RGDID: 1308751
• Length: 330
• Species: Rattus norvegicus
• Alignment Length: 344
• Identity: 134/344 - (38%)
• Similarity: 185/344 - (53%)
• Gaps: 37/344 - (10%)

  Fly   213 CVGFPGPGTGHYATFNPMQEFISGTDEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIH 277
            |:|.......|              |...|..:..:|.|||..|:::.|.:.|. ::..|::.|:
  Rat    11 CLGMISAAPTH--------------DPSFDTVWEEWKTKHGKTYNTNEEGQKRA-VWENNMKMIN 60

  Fly   278 SKN----RAKLTYTLAVNHLADKTEEELK-ARRGYKSSGIYNT---GKPFPYDVPKYKDEIPDQY 334
            ..|    :.|..::|.:|...|.|..|.: ...|::|.|...|   .:||..|:||       ..
  Rat    61 LHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQSMGPKETTIFREPFLGDIPK-------SL 118

  Fly   335 DWRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGE 399
            |||.:|.|||||:|..|||||:|..:|.|||..| |..|.||.||:|.|:||||:|||.||:||.
  Rat   119 DWREHGYVTPVKNQGQCGSCWAFSAVGSLEGQIF-KKTGKLVSLSEQNLVDCSWSYGNLGCNGGL 182

  Fly   400 DFRVYQWMLQSGGVPTEEEYGPYLGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPL 464
            ....:|::.::.|:.|.|.|. |..|||.|..|.....|.:.|||.|..::.:... |:...||:
  Rat   183 MEFAFQYVKENRGLDTGESYA-YEAQDGLCRYNPKYSAANVTGFVKVPLSEDDLMS-AVASVGPV 245

  Fly   465 SVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYG-SINGEDYWLVKNSWSTYWGNDGY 528
            ||.||:..::|.|||.|:||||.|.:  ..:|||||.|||| ..:|..||||||||...||.|||
  Rat   246 SVGIDSHHQSFRFYSGGMYYEPDCSS--TEMDHAVLVVGYGEESDGGKYWLVKNSWGEDWGMDGY 308

  Fly   529 ILMSA-KKNNCGVMTMPTY 546
            |.|:. :.||||:.|...|
  Rat   309 IKMAKDQNNNCGIATYAIY 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	15/58 (26%)
		Peptidase_C1A	331..547	CDD:239068	104/218 (48%)
Cts7l2	XP_225137.5	Inhibitor_I29	29..87	CDD:214853	15/58 (26%)
		Peptidase_C1	114..329	CDD:425470	106/226 (47%)