Protein Alignment CtsK1 and Ctsr

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_783171.2
• Gene: Ctsr / 290975
• RGDID: 631422
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 349
• Identity: 117/349 - (33%)
• Similarity: 180/349 - (51%)
• Gaps: 37/349 - (10%)

  Fly   210 SLQCVGFPGPGTGHYATFNPMQEFISGTDEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLR 274
            ::.|:|.   |:|..| |:|          .:|..:|.:|.::..:|..: |..||:.::.:|::
  Rat     8 AILCLGV---GSGALA-FDP----------SLDAEWHDWKTEYEKSYTME-EEGHRRAVWEENMK 57

  Fly   275 YIHSKNR----AKLTYTLAVNHLADKTEEELKARRGYKSSGIYNTGKPFPYDVPKYKD---EIPD 332
            .|...||    .|..:.:.:|...|.|.||.:..........:..||     :.:.:|   .:|.
  Rat    58 MIKLHNRENSLGKNGFIMEMNEFGDLTAEEFRKMMVNIPIRSHRKGK-----IIRKRDVGNVLPK 117

  Fly   333 QYDWRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDG 397
            ..|||..|.||.|::|..|.|||:|...|.:||..|.|. |.|..||.|.|:||:.:.||.||..
  Rat   118 FVDWRKKGYVTRVQNQKFCNSCWAFAVTGAIEGQMFNKT-GQLTPLSVQNLVDCTKSQGNEGCQW 181

  Fly   398 GEDFRVYQWMLQSGGVPTEEEYGPYLGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHG 462
            |:....|:::|.:||:..|..| ||.|::|.|..|.....|.|.|||::..:: :....|:...|
  Rat   182 GDPHIAYEYVLNNGGLEAEATY-PYKGKEGVCRYNPKHSKAEITGFVSLPESE-DILMEAVATIG 244

  Fly   463 PLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYG----SINGEDYWLVKNSWSTYW 523
            |:|||:|||..:|.||..|:|.||.|.|:.  ::|:||.||||    ..:|..|||:||||...|
  Rat   245 PISVAVDASFNSFGFYKKGLYDEPNCSNNT--VNHSVLVVGYGFEGNETDGNSYWLIKNSWGRKW 307

  Fly   524 GNDGYILMSAKKNN-CGVMTMPTY 546
            |..||:.:...:|| |.:.:...|
  Rat   308 GLRGYMKIPKDQNNFCAIASYAHY 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	14/58 (24%)
		Peptidase_C1A	331..547	CDD:239068	90/221 (41%)
Ctsr	NP_783171.2	Inhibitor_I29	29..87	CDD:214853	14/58 (24%)
		Peptidase_C1A	116..332	CDD:239068	90/221 (41%)