Protein Alignment CtsK1 and Ctsz

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_899159.1
• Gene: Ctsz / 252929
• RGDID: 708479
• Length: 306
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 79/279 - (28%)
• Similarity: 124/279 - (44%)
• Gaps: 62/279 - (22%)

  Fly   291 NHLADKTEEELKARRGYKSSGIYNTGKPFPYDVPKYKDEIPDQYDWR-----LYGAVTPVKDQSV 350
            :|||      |..||.|.        :|..|..|.   ::|..:|||     .|.:||  ::|.:
  Rat    42 DHLA------LLGRRTYP--------RPHEYLSPA---DLPKNWDWRNVNGVNYASVT--RNQHI 87

  Fly   351 ---CGSCWSFGTIGHLEGAFFLKNGG--NLVRLSQQALIDCSWAYGNNG-CDGGEDFRVYQWMLQ 409
               |||||:.|:...|.....:|..|  ....||.|.:|||    ||.| |:||.|..|::: ..
  Rat    88 PQYCGSCWAHGSTSALADRINIKRKGAWPSTLLSVQNVIDC----GNAGSCEGGNDLPVWEY-AH 147

  Fly   410 SGGVPTEEEYGPYLGQDGYCH----------------VNNVTLVAPIKGFVNVTSNDPNAFKLAL 458
            ..|:| :|....|..:|..|.                :.|.||.. :..:.:::..:  .....:
  Rat   148 KHGIP-DETCNNYQAKDQECDKFNQCGTCTEFKECHTIQNYTLWR-VGDYGSLSGRE--KMMAEI 208

  Fly   459 LKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYG-SINGEDYWLVKNSWSTY 522
            ..:||:|..|.|:.: .|.|:.|:|.|  .:|... ::|.:...|:| |.:|.:||:|:|||...
  Rat   209 YANGPISCGIMATER-MSNYTGGIYTE--YQNQAI-INHIISVAGWGVSNDGIEYWIVRNSWGEP 269

  Fly   523 WGNDGY--ILMSAKKNNCG 539
            ||..|:  |:.|..|...|
  Rat   270 WGERGWMRIVTSTYKGGTG 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	3/8 (38%)
		Peptidase_C1A	331..547	CDD:239068	69/239 (29%)
Ctsz	NP_899159.1	Peptidase_C1A_CathepsinX	64..305	CDD:239149	69/240 (29%)