Protein Alignment CtsK1 and cpr-6

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_741818.1
• Gene: cpr-6 / 180931
• WormBaseID: WBGene00000786
• Length: 379
• Species: Caenorhabditis elegans
• Alignment Length: 323
• Identity: 84/323 - (26%)
• Similarity: 129/323 - (39%)
• Gaps: 81/323 - (25%)

  Fly   271 QNLRYIHSKNRAKLTY---------TLAVNH--LADKTEEELKARRGYKSSGIYNTGKPFPYDVP 324
            |||.....:.|....|         .:.|||  |:.|.::.|.
 Worm    54 QNLWTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKGKQHLS---------------------- 96

  Fly   325 KYKD---EIPDQYD----WRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNL-VRLSQQ 381
            |.||   :||:.:|    |....::..::|||.|||||:||.:..:.....:.:.|.| |.||..
 Worm    97 KTKDLDLDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSAD 161

  Fly   382 ALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLGQDGY----C-HVNNVTLVAP-- 439
            .|:.|..:.| .||:||:....:::.::. |:.|...|....|...|    | |.:..|...|
 Worm   162 DLLSCCKSCG-FGCNGGDPLAAWRYWVKD-GIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPCP 224

  Fly   440 -------------IKGFVNVT--------------SNDPNAFKLALLKHGPLSVAIDASPKTFSF 477
                         :..:.:.|              .:|..|.:..|:.||||.:|.:.. :.|..
 Worm   225 HDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVY-EDFLN 288

  Fly   478 YSHGVYYEPTCKNDVDGLDHAVLAVGYGSINGEDYWLVKNSWSTYWGNDGYILMSAKKNNCGV 540
            |..|||.....|.   |..|||..:|:|..:|..||.|.|||:|.||.||:..:....:.||:
 Worm   289 YDGGVYVHTGGKL---GGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGI 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	10/39 (26%)
		Peptidase_C1A	331..547	CDD:239068	69/249 (28%)
cpr-6	NP_741818.1	Peptidase_C1A_CathepsinB	106..355	CDD:239111	69/249 (28%)