Protein Alignment CtsK1 and cpl-1

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001256718.1
• Gene: cpl-1 / 180111
• WormBaseID: WBGene00000776
• Length: 337
• Species: Caenorhabditis elegans
• Alignment Length: 302
• Identity: 122/302 - (40%)
• Similarity: 177/302 - (58%)
• Gaps: 22/302 - (7%)

  Fly   257 HSDTEHEHRKNIFRQNLRYIHSKNR----AKLTYTLAVNHLADKTEEELKARRGYK----SSGIY 313
            :|::|.:.....|.:|:.:|.:.||    .:.|:.:.:||:||....:.:...||:    .|.|.
 Worm    43 YSESEEQTYMEAFVKNMIHIENHNRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGDSRIK 107

  Fly   314 NTGKPF-PYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLVR 377
            |:.... |::|     ::||:.|||....||.||:|.:|||||:|...|.|||....|. |.||.
 Worm   108 NSSSFLAPFNV-----QVPDEVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHARKL-GQLVS 166

  Fly   378 LSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLGQDGYCHVNNVTLVAPIKG 442
            ||:|.|:|||..|||:||:||...:.::::..:.||.|||.| ||.|:|..||.|..|:.|..||
 Worm   167 LSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESY-PYKGRDMKCHFNKKTVGADDKG 230

  Fly   443 FVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYGS- 506
            :|:....|....|:|:...||:|:||||..::|..|..||||:..|.:  :.|||.||.||||:
 Worm   231 YVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSS--EELDHGVLLVGYGTD 293

  Fly   507 -INGEDYWLVKNSWSTYWGNDGYILMSAKKNN-CGVMTMPTY 546
             .:| |||:|||||...||..|||.::..:|| |||.|..:|
 Worm   294 PEHG-DYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASY 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	12/46 (26%)
		Peptidase_C1A	331..547	CDD:239068	103/219 (47%)
cpl-1	NP_001256718.1	Inhibitor_I29	32..91	CDD:462410	12/47 (26%)
		Peptidase_C1	120..336	CDD:425470	103/220 (47%)