Protein Alignment CtsK1 and F26E4.3

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_492593.2
• Gene: F26E4.3 / 172827
• WormBaseID: WBGene00009158
• Length: 452
• Species: Caenorhabditis elegans
• Alignment Length: 279
• Identity: 79/279 - (28%)
• Similarity: 118/279 - (42%)
• Gaps: 59/279 - (21%)

  Fly   309 SSGI-YNTGKPFPYDVPKYKDEI-------PDQYDWR-LYG-AVTPVKDQSVCGSCWSFGTIGHL 363
            |.|| |..|..||....:..:||       |:.:|.| .:| .:.||.||..|||.||..|....
 Worm   155 SDGIKYRLGTLFPERSVQNMNEILIKPRELPEHFDARDKWGPLIHPVADQGDCGSSWSVSTTAIS 219

  Fly   364 EGAFFLKNGGNL-VRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYL-GQD 426
            .....:.:.|.: ..||.|.|:.|: .:...||:||...|.: |.::..||..:..| ||: ||.
 Worm   220 SDRLAIISEGRINSTLSSQQLLSCN-QHRQKGCEGGYLDRAW-WYIRKLGVVGDHCY-PYVSGQS 281

  Fly   427 ---GYCHVNNVTLVAPIKGFVN-------VTSNDPNAFKLA---------------LLKHGPLSV 466
               |:|       :.|.:.:.|       ..|.|..|||:.               |:.:||:.
 Worm   282 REPGHC-------LIPKRDYTNRQGLRCPSGSQDSTAFKMTPPYKVSSREEDIQTELMTNGPVQ- 338

  Fly   467 AIDASPKTFSFYSHGVYY------EPTCKNDVDGLDHAVLAVGYGSINGE----DYWLVKNSWST 521
            |.....:.|..|:.|||.      :....:..:|. |:|..:|:|..:..    .|||..|||.|
 Worm   339 ATFVVHEDFFMYAGGVYQHSDLAAQKGASSVAEGY-HSVRVLGWGVDHSTGKPIKYWLCANSWGT 402

  Fly   522 YWGNDGYILMSAKKNNCGV 540
            .||.|||..:...:|:|.:
 Worm   403 QWGEDGYFKVLRGENHCEI 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853
		Peptidase_C1A	331..547	CDD:239068	70/249 (28%)
F26E4.3	NP_492593.2	Somatomedin_B	37..83	CDD:460034
		Peptidase_C1A_CathepsinB	185..428	CDD:239111	70/249 (28%)