DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 26-29-p and cpz-1

DIOPT Version :9

Sequence 1:	NP_620470.1	Gene:	26-29-p / 39547	FlyBaseID:	FBgn0250848	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	NP_491023.2	Gene:	cpz-1 / 171829	WormBaseID:	WBGene00000788	Length:	306	Species:	Caenorhabditis elegans

Alignment Length:	277	Identity:	77/277 - (27%)
Similarity:	118/277 - (42%)	Gaps:	59/277 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 RRGYKSSGIY-NTGKPFP-------YDVPKY-KDEIPDQYDWRLYGAV---TPVKDQSV---CGS 353
            |..|...|.| .||:.|.       |:...: .:::|..:|||....:   :..::|.:   |||
Worm    30 RNRYNLKGCYKQTGRVFEHKRYDRIYETEDFDSEDLPKTWDWRDANGINYASADRNQHIPQYCGS 94

  Fly   354 CWSFGTIGHLEGAFFL--KNGGNLVRLSQQALIDCSWAYGNNGC-DGGEDFRVYQWMLQSGGVPT 415
            ||:||....|.....:  ||......||.|.:||||   |...| .|||...||:: ....|:|
Worm    95 CWAFGATSALADRINIKRKNAWPQAYLSVQEVIDCS---GAGTCVMGGEPGGVYKY-AHEHGIP- 154

  Fly   416 EEEYGPYLGQDGYC---------------HVNNVTL-----VAPIKGFVNVTSNDPNAFKLALLK 460
            .|....|..:||.|               .:.|.||     ...:.|:        ...|..:..
Worm   155 HETCNNYQARDGKCDPYNRCGSCWPGECFSIKNYTLYKVSEYGTVHGY--------EKMKAEIYH 211

  Fly   461 HGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAVGYG--SINGEDYWLVKNSWSTYW 523
            .||::..| |:.|.|..|:.|:|.|.|   |.| :||.:...|:|  ..:|.:||:.:|||...|
Worm   212 KGPIACGI-AATKAFETYAGGIYKEVT---DED-IDHIISVHGWGVDHESGVEYWIGRNSWGEPW 271

  Fly   524 GNDGYI-LMSAKKNNCG 539
            |..|:. :::::..|.|
Worm   272 GEHGWFKIVTSQYKNAG 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853
26-29-p	NP_620470.1	Peptidase_C1A	331..547	CDD:239068	69/241 (29%)
cpz-1	NP_491023.2	Peptidase_C1A_CathepsinX	65..305	CDD:239149	69/242 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820