Protein Alignment 26-29-p and CTSW

DIOPT Version :9

• Sequence 1: NP_620470.1
• Gene: 26-29-p / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001326.3
• Gene: CTSW / 1521
• HGNCID: 2546
• Length: 376
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 97/330 - (29%)
• Similarity: 156/330 - (47%)
• Gaps: 39/330 - (11%)

  Fly   243 KAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKNRAKL-TYTLAVNHLADKTEEELKARRG 306
            :||..|:.:...:|.|..||.||.:||..||..........| |....|...:|.||||.....|
Human    40 EAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYG 104

  Fly   307 YK--SSGIYNTGKPFPYDVPKYKDEIPDQYDWR-LYGAVTPVKDQSVCGSCWSFGTIGHLEGAFF 368
            |:  :.|:.:.|:....:.|  ::.:|...||| :..|::|:|||..|..||:....|::|..:.
Human   105 YRRAAGGVPSMGREIRSEEP--EESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWR 167

  Fly   369 LKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLG--QDGYCHV 431
            : :..:.|.:|.|.|:||...  .:||.||..:..:..:|.:.|:.:|::| |:.|  :...||.
Human   168 I-SFWDFVDVSVQELLDCGRC--GDGCHGGFVWDAFITVLNNSGLASEKDY-PFQGKVRAHRCHP 228

  Fly   432 NNVTLVAPIKGFVNVTSNDPNAFKLA--LLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDG 494
            .....||.|:.|:.:.:|:   .::|  |..:||::|.|:..|  ...|..||........|...
Human   229 KKYQKVAWIQDFIMLQNNE---HRIAQYLATYGPITVTINMKP--LQLYRKGVIKATPTTCDPQL 288

  Fly   495 LDHAVLAVGYGSINGED--------------------YWLVKNSWSTYWGNDGYILMSAKKNNCG 539
            :||:||.||:||:..|:                    ||::||||...||..||..:....|.||
Human   289 VDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCG 353

  Fly   540 VMTMP 544
            :...|
Human   354 ITKFP 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	18/55 (33%)
		Peptidase_C1A	331..547	CDD:239068	71/239 (30%)
CTSW	NP_001326.3	Inhibitor_I29	42..98	CDD:214853	18/55 (33%)
		Peptidase_C1A	129..358	CDD:239068	70/237 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810