Protein Alignment 26-29-p and CTSO

DIOPT Version :9

• Sequence 1: NP_620470.1
• Gene: 26-29-p / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001325.1
• Gene: CTSO / 1519
• HGNCID: 2542
• Length: 321
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 97/298 - (32%)
• Similarity: 141/298 - (47%)
• Gaps: 43/298 - (14%)

  Fly   263 EHRKNIFRQNL---RYIH----SKNRAKLTYTLAVNHLADKTEEELKARRGYKSSGIYNTGKPFP 320
            |.....||::|   ||::    |:|.   |....:|..:....||.||        ||...||..
Human    38 EREAAAFRESLNRHRYLNSLFPSENS---TAFYGINQFSYLFPEEFKA--------IYLRSKPSK 91

  Fly   321 YDVPKYKDEI---------PDQYDWRLYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLKNGGNLV 376
            :  |:|..|:         |.::|||....||.|::|.:||.||:|..:|.:|.|:.:| |..|.
Human    92 F--PRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIK-GKPLE 153

  Fly   377 RLSQQALIDCSWAYGNNGCDGGEDFRVYQWM--LQSGGVPTEEEYGPYLGQDGYCHVNNVTLVA- 438
            .||.|.:||||  |.|.||:||.......|:  :|...| .:.|| |:..|:|.||..:.:...
Human   154 DLSVQQVIDCS--YNNYGCNGGSTLNALNWLNKMQVKLV-KDSEY-PFKAQNGLCHYFSGSHSGF 214

  Fly   439 PIKGFVNVT-SNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHAVLAV 502
            .|||:.... |:..:....|||..|||.|.:||  .::..|..|:........:.   :||||..
Human   215 SIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDA--VSWQDYLGGIIQHHCSSGEA---NHAVLIT 274

  Fly   503 GYGSINGEDYWLVKNSWSTYWGNDGYILMSAKKNNCGV 540
            |:.......||:|:|||.:.||.|||..:....|.||:
Human   275 GFDKTGSTPYWIVRNSWGSSWGVDGYAHVKMGSNVCGI 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	10/43 (23%)
		Peptidase_C1A	331..547	CDD:239068	76/214 (36%)
CTSO	NP_001325.1	Peptidase_C1A	109..319	CDD:239068	76/214 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820