Protein Alignment 26-29-p and CTSL

DIOPT Version :9

• Sequence 1: NP_620470.1
• Gene: 26-29-p / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001244900.1
• Gene: CTSL / 1514
• HGNCID: 2537
• Length: 333
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 122/317 - (38%)
• Similarity: 173/317 - (54%)
• Gaps: 32/317 - (10%)

  Fly   243 KAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKNR----AKLTYTLAVNHLADKTEEELKA 303
            ||.|:  |.:|:     .|...|:.::.:|::.|...|:    .|.::|:|:|...|.|.||.:
Human    33 KAMHN--RLYGM-----NEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFR- 89

  Fly   304 RRGYKSSGIYN----TGKPFPYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGTIGHLE 364
               ...:|..|    .||.|  ..|.:. |.|...|||..|.|||||:|..|||||:|...|.||
Human    90 ---QVMNGFQNRKPRKGKVF--QEPLFY-EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALE 148

  Fly   365 GAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLGQDGYC 429
            |..|.|. |.|:.||:|.|:|||...||.||:||.....:|::..:||:.:||.| ||...:..|
Human   149 GQMFRKT-GRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESY-PYEATEESC 211

  Fly   430 HVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDG 494
            ..|....||...|||::...: .|...|:...||:||||||..::|.||..|:|:||.|.:  :.
Human   212 KYNPKYSVANDTGFVDIPKQE-KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSS--ED 273

  Fly   495 LDHAVLAVGYGSINGED----YWLVKNSWSTYWGNDGYILMSA-KKNNCGVMTMPTY 546
            :||.||.||||..:.|.    ||||||||...||..||:.|:. ::|:||:.:..:|
Human   274 MDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASY 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	14/58 (24%)
		Peptidase_C1A	331..547	CDD:239068	97/221 (44%)
CTSL	NP_001244900.1	Inhibitor_I29	29..87	CDD:214853	16/60 (27%)
		Peptidase_C1	114..332	CDD:395062	97/222 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149678
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.760