Protein Alignment CtsK1 and Ctsw

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_034115.2
• Gene: Ctsw / 13041
• MGIID: 1338045
• Length: 371
• Species: Mus musculus
• Alignment Length: 323
• Identity: 88/323 - (27%)
• Similarity: 138/323 - (42%)
• Gaps: 28/323 - (8%)

  Fly   243 KAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKNRAKL-TYTLAVNHLADKTEEELKARRG 306
            :.|..|:.:...:|.:..|:..|.:||..||.......:..| |........:|.||||.....|
Mouse    38 EVFKLFQIRFNRSYWNPAEYTRRLSIFAHNLAQAQRLQQEDLGTAEFGETPFSDLTEEEFGQLYG 102

  Fly   307 YKSSGIYNTGKPFPYDVPKYKDEIPDQYDWR-LYGAVTPVKDQSVCGSCWSFGTIGHLEGAFFLK 370
            .:.|...........:...:.:.:|...||| ....::.||:|..|..||:.....:::..:.:|
Mouse   103 QERSPERTPNMTKKVESNTWGESVPRTCDWRKAKNIISSVKNQGSCKCCWAMAAADNIQALWRIK 167

  Fly   371 NGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLG--QDGYCHVNN 433
            : ...|.:|.|.|:||...  .|||:||..:..|..:|.:.|:.:|::| |:.|  :...|....
Mouse   168 H-QQFVDVSVQELLDCERC--GNGCNGGFVWDAYLTVLNNSGLASEKDY-PFQGDRKPHRCLAKK 228

  Fly   434 VTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEPTCKNDVDGLDHA 498
            ...||.|:.| .:.||:..|....|..|||::|.|:.  |....|..||........|...:||:
Mouse   229 YKKVAWIQDF-TMLSNNEQAIAHYLAVHGPITVTINM--KLLQHYQKGVIKATPSSCDPRQVDHS 290

  Fly   499 VLAVGYGS-----------------INGEDYWLVKNSWSTYWGNDGYILMSAKKNNCGVMTMP 544
            ||.||:|.                 .:...||::||||..:||..||..:....|.|||...|
Mouse   291 VLLVGFGKEKEGMQTGTVLSHSRKRRHSSPYWILKNSWGAHWGEKGYFRLYRGNNTCGVTKYP 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	14/55 (25%)
		Peptidase_C1A	331..547	CDD:239068	70/234 (30%)
Ctsw	NP_034115.2	Inhibitor_I29	40..96	CDD:214853	14/55 (25%)
		Peptidase_C1A	127..356	CDD:239068	70/234 (30%)