Protein Alignment CtsK1 and Cts3

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_081182.2
• Gene: Cts3 / 117066
• MGIID: 2151929
• Length: 332
• Species: Mus musculus
• Alignment Length: 328
• Identity: 108/328 - (32%)
• Similarity: 166/328 - (50%)
• Gaps: 39/328 - (11%)

  Fly   238 DEHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKN----RAKLTYTLAVNHLADKTE 298
            |..:|..:..:|.|:|..|..:.|.:.|. ::.:|::.|...|    ..|..:|:.:|...|.|.
Mouse    22 DPILDAEWQKWKIKYGKTYSLEEEGQKRA-VWEENMKKIKLHNGENGLGKHGFTMEMNAFGDMTL 85

  Fly   299 EELK----------ARRGYKSSGIYNTGKPFPYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGS 353
            ||.:          .::| ||     ..|....::||:       .:|:..|.||||:.|..|.|
Mouse    86 EEFRKEMIEIPVPTVKKG-KS-----VQKRLSVNLPKF-------INWKKRGYVTPVRTQIACNS 137

  Fly   354 CWSFGTIGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEE 418
            ||:....|.:||..|.|. |.|:.||.|.|:||   ...:||..|.....::::::.||:.:|..
Mouse   138 CWAISVTGAIEGQMFRKT-GQLIPLSVQNLVDC---VDGSGCHAGSVLDSFKYLMEKGGLESEAT 198

  Fly   419 YGPYLGQDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVY 483
            | ||..:.|.|..|.....|.|.||..:.:|:.:... |:...||:||.|||..::|.||..|:|
Mouse   199 Y-PYEDKQGSCRYNPENSTASITGFEFIPNNEVDLMS-AVASLGPISVVIDAWHESFLFYKRGIY 261

  Fly   484 YEPTCKNDVDGLDHAVLAVGYGSI----NGEDYWLVKNSWSTYWGNDGYILMSAKK-NNCGVMTM 543
            |||.|.|.:..|.||||.||||.|    .|..||::|||..|.||..||:.::..: |:||:.::
Mouse   262 YEPNCNNSLFALRHAVLLVGYGFIGRESEGRKYWIIKNSLGTKWGYKGYMKIAKDQGNHCGIASL 326

  Fly   544 PTY 546
            |.:
Mouse   327 PVF 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	14/58 (24%)
		Peptidase_C1A	331..547	CDD:239068	84/221 (38%)
Cts3	NP_081182.2	Inhibitor_I29	29..87	CDD:214853	14/58 (24%)
		Peptidase_C1A	115..330	CDD:239068	86/228 (38%)