DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 26-29-p and asic5

DIOPT Version :9

Sequence 1:	NP_620470.1	Gene:	26-29-p / 39547	FlyBaseID:	FBgn0250848	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	XP_017951381.2	Gene:	asic5 / 100498195	XenbaseID:	XB-GENE-983430	Length:	852	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	101/313 - (32%)
Similarity:	151/313 - (48%)	Gaps:	34/313 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 AFHHFKRKHGVAYHSDTE-HEHRKNIF-----RQNLRYIHSKNRAKLTYTL------AVNHLADK 296
            ||..|.:|:|..|...:: .:.|..||     |||  |:   |...|...|      .:|..:|.
Frog    65 AFLDFIQKYGRGYKDGSQVFQERYQIFLKSTERQN--YL---NAIALPTNLTSAAHYGINQFSDL 124

  Fly   297 TEEEL--KARRGYKSSGIYNTGKPFPYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGT 359
            :.||.  ...|.: .:|.|.:.|||.....:|  .:|.::|||....|||||:|..||:||:|..
Frog   125 SAEEFFYTYLRSF-PTGNYTSNKPFKNSAQQY--FLPLRFDWRDKKLVTPVKNQLSCGACWAFSV 186

  Fly   360 IGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQS-GGVPTEEEYGPYL 423
            :|.:|.|:.:| ...|..||.|.:||||  |.::||:||......:|:.|: ..:....||. :.
Frog   187 VGAVESAYAIK-WHTLEELSVQQVIDCS--YLDSGCNGGSTNGALKWLYQTKTKLVRASEYN-FK 247

  Fly   424 GQDGYCHVNNVT-LVAPIKGF-VNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEP 486
            .:.|.||....| ....|.|: ....|...:|....|:..||:.|.::|  .::..|..|: .:.
Frog   248 AKTGLCHYFPKTDFGVSINGYETQDFSGTEDAMMKMLVDLGPMVVIVNA--VSWQDYLGGI-IQH 309

  Fly   487 TCKNDVDGLDHAVLAVGYGSINGEDYWLVKNSWSTYWGNDGYILMSAKKNNCG 539
            .|.:...  :||||.:||.......||:|||||.|.||.|||:.:...:|.||
Frog   310 HCSSGAP--NHAVLVIGYDKTGDTPYWIVKNSWGTAWGADGYVYIKMGENICG 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	17/66 (26%)
26-29-p	NP_620470.1	Peptidase_C1A	331..547	CDD:239068	74/212 (35%)
asic5	XP_017951381.2	Inhibitor_I29	66..129	CDD:400519	18/67 (27%)
		Peptidase_C1A	158..360	CDD:239068	72/210 (34%)
		ASC	387..816	CDD:395688
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010