Protein Alignment CtsK1 and asic5

DIOPT Version :10

• Sequence 1: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: XP_017951381.2
• Gene: asic5 / 100498195
• XenbaseID: XB-GENE-983430
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 313
• Identity: 101/313 - (32%)
• Similarity: 151/313 - (48%)
• Gaps: 34/313 - (10%)

  Fly   244 AFHHFKRKHGVAYHSDTE-HEHRKNIF-----RQNLRYIHSKNRAKLTYTL------AVNHLADK 296
            ||..|.:|:|..|...:: .:.|..||     |||  |:   |...|...|      .:|..:|.
 Frog    65 AFLDFIQKYGRGYKDGSQVFQERYQIFLKSTERQN--YL---NAIALPTNLTSAAHYGINQFSDL 124

  Fly   297 TEEEL--KARRGYKSSGIYNTGKPFPYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGT 359
            :.||.  ...|.: .:|.|.:.|||.....:|  .:|.::|||....|||||:|..||:||:|..
 Frog   125 SAEEFFYTYLRSF-PTGNYTSNKPFKNSAQQY--FLPLRFDWRDKKLVTPVKNQLSCGACWAFSV 186

  Fly   360 IGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQS-GGVPTEEEYGPYL 423
            :|.:|.|:.:| ...|..||.|.:||||  |.::||:||......:|:.|: ..:....||. :.
 Frog   187 VGAVESAYAIK-WHTLEELSVQQVIDCS--YLDSGCNGGSTNGALKWLYQTKTKLVRASEYN-FK 247

  Fly   424 GQDGYCHVNNVT-LVAPIKGF-VNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVYYEP 486
            .:.|.||....| ....|.|: ....|...:|....|:..||:.|.::|  .::..|..|: .:.
 Frog   248 AKTGLCHYFPKTDFGVSINGYETQDFSGTEDAMMKMLVDLGPMVVIVNA--VSWQDYLGGI-IQH 309

  Fly   487 TCKNDVDGLDHAVLAVGYGSINGEDYWLVKNSWSTYWGNDGYILMSAKKNNCG 539
            .|.:...  :||||.:||.......||:|||||.|.||.|||:.:...:|.||
 Frog   310 HCSSGAP--NHAVLVIGYDKTGDTPYWIVKNSWGTAWGADGYVYIKMGENICG 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	17/66 (26%)
		Peptidase_C1A	331..547	CDD:239068	74/212 (35%)
asic5	XP_017951381.2	Inhibitor_I29	66..129	CDD:462410	18/67 (27%)
		Peptidase_C1A	158..360	CDD:239068	72/210 (34%)
		ASC	387..816	CDD:459966