DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 26-29-p and si:dkey-267n13.1

DIOPT Version :9

Sequence 1:	NP_620470.1	Gene:	26-29-p / 39547	FlyBaseID:	FBgn0250848	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	XP_002665630.2	Gene:	si:dkey-267n13.1 / 100001286	ZFINID:	ZDB-GENE-141211-35	Length:	292	Species:	Danio rerio

Alignment Length:	281	Identity:	98/281 - (34%)
Similarity:	146/281 - (51%)	Gaps:	9/281 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PKWDPNYIVKGTLYIPYAEIAEPFYAWYDKNTRRSRIDYYGGMVKTYQLAGEGQYGTLLKLAPIT 87
            |.:...|.|||.:.:|..||.|||.||||....|||||||.|.|.|:.:..:..||.:.::.|:
Zfish    17 PDFGKMYHVKGVISLPSYEIEEPFEAWYDFERNRSRIDYYNGTVCTFLIGNDLDYGAIYQIRPV- 80

  Fly    88 TKTENNKLTCLQVNGTADQAVDIQSILPDAKPFSLVGTESFLGYTCDKFRLESTIGQKKNIYTLW 152
              ...|.:.|.|:.||.::.:..||.:||.:.|.....:...|..|:.::..:..|.|||.|.||
Zfish    81 --LPTNDIKCFQLKGTKEEPIQPQSAMPDVQGFEFEKMDYHKGSRCEVWKTVTEAGHKKNTYRLW 143

  Fly   153 VRYKKSPHYPSSRMPIPVRYEMRGYNTLLGSHYDHYYLDYDSYEHDDIPNEVFEIDDSLQCVGFP 217
            |...:....|::    |.|:||.|:||||.||.|.|.::|..:.....| :||.......|..||
Zfish   144 VTRPEGNDAPAT----PHRFEMEGFNTLLDSHNDKYSIEYSDFCTQSEP-DVFTPPAGFTCEEFP 203

  Fly   218 GPGTGHYATFNPMQEFISGTD-EHVDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKNR 281
            .|...|....||:|:::|... .|..:.|..||.|....|.|:.|||.|:..|.|:.|:::|.||
Zfish   204 DPPEEHQILANPIQDYVSTNPVSHAHRMFGPFKEKFNRQYKSEKEHEKREINFVQSFRFVNSTNR 268

  Fly   282 AKLTYTLAVNHLADKTEEELK 302
            ..|::|:.:|..||.:..|.:
Zfish   269 KGLSFTVGINDRADWSRAETR 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	21/54 (39%)
26-29-p	NP_620470.1	Peptidase_C1A	331..547	CDD:239068
si:dkey-267n13.1	XP_002665630.2	Inhibitor_I29	232..287	CDD:285458	21/54 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581678
Domainoid	1	1.000	194	1.000	Domainoid score	I3120
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850