Protein Alignment Hsc70-1 and ECM10

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_010884.1
• Gene: ECM10 / 856682
• SGDID: S000000756
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 601
• Identity: 296/601 - (49%)
• Similarity: 404/601 - (67%)
• Gaps: 36/601 - (5%)

  Fly     3 KLP--AVGIDLGTTYSCVGVFQHGKV-EIIANDQGNRTTPSYVAFT-ESERLIGDAAKNQVAMNP 63
            |:|  .:|||||||.|.|.:.: ||| .||.|.:|:|||||.|||| :.|||:|:.||.|..:|.
Yeast    24 KIPDAVIGIDLGTTNSAVAIME-GKVPRIIENAEGSRTTPSVVAFTKDGERLVGEPAKRQSVINS 87

  Fly    64 NNTIFDAKRLIGRRFDDATVQSDMKHWPFEVFA-ENGKPRIRVEYKGERKSFYPEEVSSMVLTKM 127
            .||:|..||||||||:||.||.|:...||::.. .||...:    :...:::.|.::...:|.||
Yeast    88 ENTLFATKRLIGRRFEDAEVQRDINQVPFKIVKHSNGDAWV----EARNRTYSPAQIGGFILNKM 148

  Fly   128 RETAEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSE 192
            :|||||||..:|.:|||||||||||:|||||||||.|.||||||::|||||||:||||||   ||
Yeast   149 KETAEAYLAKSVKNAVVTVPAYFNDAQRQATKDAGQIIGLNVLRVVNEPTAAALAYGLDK---SE 210

  Fly   193 RNVL-IFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQN 256
            ..|: :|||||||||:|:|.|::||||||:|.|||||||||||..|:...:..|:::...||..:
Yeast   211 PKVIAVFDLGGGTFDISILDIDNGIFEVKSTNGDTHLGGEDFDIYLLQEIISHFKKETGIDLSND 275

  Fly   257 KRALRRLRTACERAKRTLSSSTQASIEIDSLFEGVD------FYTSVTRARFEELNGDLFRGTME 315
            :.|::|:|.|.|:||..|||:  .|.||:..|...|      .....:|.:.|.:...|...|::
Yeast   276 RMAVQRIREAAEKAKIELSST--LSTEINLPFITADAAGPKHIRMPFSRVQLENITAPLIDRTVD 338

  Fly   316 PVAKALRDAKMDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAIL 380
            ||.|||:||::....|.|::||||.:|:|||...::..| ||:.:|::|||||||.|||:|||:|
Yeast   339 PVKKALKDARITASDISDVLLVGGMSRMPKVADTVKKLF-GKDASKAVNPDEAVALGAAIQAAVL 402

  Fly   381 HGDKSEAVQDLLLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEG 445
            .|:    |.|:||||||||||||||.|||.|.||.||:|||.|::|||:|.|..|..|.::||:|
Yeast   403 SGE----VTDVLLLDVTPLSLGIETLGGVFTKLIPRNSTIPNKKSQIFSTAASGQTSVEVKVFQG 463

  Fly   446 ERAMTRDNNSLGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRL 510
            ||.:.:||..:|.|.|:.|||||:|.||:|||||||||||:||:|.:.::.|::.||:....| |
Yeast   464 ERELVKDNKLIGNFTLAGIPPAPKGTPQIEVTFDIDANGIINVSAKDLASHKDSSITVAGASG-L 527

  Fly   511 SKEDIERMVNDAEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSS 575
            |..:|:||||:||.|:..|..:|:.|...|:.:    ||.:  |.|:....|.....:|..||..
Yeast   528 SDTEIDRMVNEAERYKNQDRARRNAIETANKAD----QLAN--DTENSIKEFEGKLDKTDSQRLK 586

  Fly   576 ETIAWLDANQLAERQE 591
            :.|:.|  .:|..|.:
Yeast   587 DQISSL--RELVSRSQ 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	296/601 (49%)
ECM10	NP_010884.1	dnaK	29..644	CDD:234715	294/596 (49%)