Protein Alignment Hsc70-1 and SSZ1

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_011931.2
• Gene: SSZ1 / 856461
• SGDID: S000001106
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 567
• Identity: 164/567 - (28%)
• Similarity: 266/567 - (46%)
• Gaps: 93/567 - (16%)

  Fly     5 PAVGIDLGTTYSCVG-VFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIF 68
            |.:||..|.|.|.:. :.....|::|||..|.|..||.:::...:...|..|..|:..||.|||.
Yeast     4 PVIGITFGNTSSSIAYINPKNDVDVIANPDGERAIPSALSYVGEDEYHGGQALQQLIRNPKNTII 68

  Fly    69 DAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYK---------GERKSFYPEEVSSMVL 124
            :.:..||..||...|..          ..||.|.:.|:.|         |:.:....:||.|..|
Yeast    69 NFRDFIGLPFDKCDVSK----------CANGAPAVEVDGKVGFVISRGEGKEEKLTVDEVVSRHL 123

  Fly   125 TKMRETAEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQG 189
            .:::..||.|:|..|.:||:|||..|::.|:.|.|.:.|..||.:::.||||:||.:|:......
Yeast   124 NRLKLAAEDYIGSAVKEAVLTVPTNFSEEQKTALKASAAKIGLQIVQFINEPSAALLAHAEQFPF 188

  Fly   190 TSERNVLIFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLG 254
            ..:.||::.|.||...|.:|:.:.:|||.:.|||.|..|||::.|..||.:|..|||:|::.:..
Yeast   189 EKDVNVVVADFGGIRSDAAVIAVRNGIFTILATAHDLSLGGDNLDTELVEYFASEFQKKYQANPR 253

  Fly   255 QNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAK 319
            :|.|:|.:|:......|:|||::|.|:|.||||.:|.|::.|:.|.|:|.:...:|......|..
Yeast   254 KNARSLAKLKANSSITKKTLSNATSATISIDSLADGFDYHASINRMRYELVANKVFAQFSSFVDS 318

  Fly   320 ALRDAKMDKGQIHDIVLVGGSTRIPKVQRLLQ-------DFFNGKELNKSINPDEAVAYGAAVQA 377
            .:..|::|...|..::|.||.:..||:...|:       :....:..|.|.||:|..|.|||:||
Yeast   319 VIAKAELDPLDIDAVLLTGGVSFTPKLTTNLEYTLPESVEILGPQNKNASNNPNELAASGAALQA 383

  Fly   378 AILH----GDKSEAVQDLLLLDVTP---LSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQ 435
            .::.    .:.:||:|.:::  .||   ..:|:..|.|....::...|:.|.::.   .|....:
Yeast   384 RLISDYDADELAEALQPVIV--NTPHLKKPIGLIGAKGEFHPVLLAETSFPVQKK---LTLKQAK 443

  Fly   436 PGVLIQVFEGERAMTRDNNSLGKFELSAIPPAPR------------------------------- 469
            ...||.|:||:.          ..|...:.|.|:
Yeast   444 GDFLIGVYEGDH----------HIEEKTLEPIPKEENAEEDDESEWSDDEPEVVREKLYTLGTKL 498

  Fly   470 ---GVPQ---VEVTFDIDANGILNVTALEKSTGKENRITITNDKGRL 510
               |:..   ||:.|:|:.:|.|.|||.:..||  |.:     ||.|
Yeast   499 MELGIKNANGVEIIFNINKDGALRVTARDLKTG--NAV-----KGEL 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	164/567 (29%)
SSZ1	NP_011931.2	ASKHA_NBD_HSP70_ScSsz1p-like	4..386	CDD:466830	129/391 (33%)