Protein Alignment Hsc70-1 and SSE1

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_015219.1
• Gene: SSE1 / 855998
• SGDID: S000006027
• Length: 693
• Species: Saccharomyces cerevisiae
• Alignment Length: 645
• Identity: 183/645 - (28%)
• Similarity: 320/645 - (49%)
• Gaps: 72/645 - (11%)

  Fly     8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIFDAKR 72
            |:|||...|.:.|.::..::|:.|:..||:|||.|.|....|.:|:..||:...|..||:.:.||
Yeast     6 GLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPKNRYLGETGKNKQTSNIKNTVANLKR 70

  Fly    73 LIGRRFDDATVQSDMKHWPFE-VFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAYLG 136
            :||..:.....:.:.||:..: |..::.|....|.:.||:..|...::::|.:.|:::|.:....
Yeast    71 IIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDTVKQDTK 135

  Fly   137 GTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDK----QGTSERNVLI 197
            ..:||..:.||.::.:.||....||..|||||.:||:|:.|||.::||:.|    :|..:..::.
Yeast   136 ANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTAAGVSYGIFKTDLPEGEEKPRIVA 200

  Fly   198 F-DLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALR 261
            | |:|..::..|::..:.|..:|..||.|.|.||.|||..:..||..||:.|:|.|:.:|.:|..
Yeast   201 FVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDFDLAITEHFADEFKTKYKIDIRENPKAYN 265

  Fly   262 RLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKM 326
            |:.||.|:.|:.||::|.|...::|:...||..:.::|...|||...|.....|||.|||..||:
Yeast   266 RILTAAEKLKKVLSANTNAPFSVESVMNDVDVSSQLSREELEELVKPLLERVTEPVTKALAQAKL 330

  Fly   327 DKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDL 391
            ...::..:.::||:||||.:::.:.:.| ||.|:.::|.|||:|.|||...|| | ..:..|:..
Yeast   331 SAEEVDFVEIIGGTTRIPTLKQSISEAF-GKPLSTTLNQDEAIAKGAAFICAI-H-SPTLRVRPF 392

  Fly   392 LLLDVTPLSLG--------------IETAGGVM--TTLIKRNTT----IPTKQTQIFTTYADNQP 436
            ...|:.|.|:.              :..||...  |.||..|.|    :....|.| |....|.|
Yeast   393 KFEDIHPYSVSYSWDKQVEDEDHMEVFPAGSSFPSTKLITLNRTGDFSMAASYTDI-TQLPPNTP 456

  Fly   437 GVL-------IQVFEGERAMTRDNNSLGKFELSAIPPAPRGVPQVEVTFDIDANGI-----LNVT 489
            ..:       :|:.||:.::.      .|.:|..   .|.|:..:|..:.|:...:     |...
Yeast   457 EQIANWEITGVQLPEGQDSVP------VKLKLRC---DPSGLHTIEEAYTIEDIEVEEPIPLPED 512

  Fly   490 ALEKSTGKENRITITNDKGRLSKEDIERMVN----DAEAYRQADEQQRDRI----------NAKN 540
            |.|.:..:..::|.|     :.|:|:..:.:    ||:...:..|::.:.:          :.||
Yeast   513 APEDAEQEFKKVTKT-----VKKDDLTIVAHTFGLDAKKLNELIEKENEMLAQDKLVAETEDRKN 572

  Fly   541 QLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWL-DANQLAERQEFEHKQQEL 599
            .||.|.:.||..|::|: :...|.|::..:|...::...|| |....:.:.::..|.:||
Yeast   573 TLEEYIYTLRGKLEEEY-APFASDAEKTKLQGMLNKAEEWLYDEGFDSIKAKYIAKYEEL 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	183/645 (28%)
SSE1	NP_015219.1	ASKHA_ATPase-like	4..644	CDD:483947	183/645 (28%)