Protein Alignment Hsc70-1 and SSE2

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_009728.1
• Gene: SSE2 / 852467
• SGDID: S000000373
• Length: 693
• Species: Saccharomyces cerevisiae
• Alignment Length: 654
• Identity: 182/654 - (27%)
• Similarity: 313/654 - (47%)
• Gaps: 68/654 - (10%)

  Fly     8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIFDAKR 72
            |:|||...|.:.|.::..::::.|:..||:|||.|.|....|.:|::.|.:...|..||:.:.||
Yeast     6 GLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGFGPRNRYLGESGKTKQTSNVKNTVENLKR 70

  Fly    73 LIGRRFDDATVQSDMKHWPFE-VFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAYLG 136
            :||.:|.|.....:.|.:..: |..:|||..:.||:.|:...|...::::|.:.|::.|.:....
Yeast    71 IIGLKFKDPEFDIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHTVQEETK 135

  Fly   137 GTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL---DKQGTSE--RNVL 196
            .::||..:.||.::::.||....||..|||||.:||:|:.||||::||:   |..|..|  |.:.
Yeast   136 SSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPRIIG 200

  Fly   197 IFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALR 261
            :.|:|..|:..|::....|..:|..||.|.|.||.|||..:..||..:|:.|:|.|:.:|.:|..
Yeast   201 LVDIGHSTYTCSIMAFRKGEMKVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPKAYN 265

  Fly   262 RLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKM 326
            |:..|.|:.|:.||::|.|...::|:.:.:|..:.::|...|||...|.:....|:..||..||:
Yeast   266 RILIAAEKLKKVLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNALAQAKL 330

  Fly   327 DKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDL 391
            ....|..:.::||:||||.:::.:.|.| ||.|:.::|.|||||.|||...|| | ..:..|:..
Yeast   331 TVNDIDFVEIIGGTTRIPVLKKSISDVF-GKPLSSTLNQDEAVAKGAAFICAI-H-SPTLRVRPF 392

  Fly   392 LLLDVTPLSLGIETAGGV----MTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRD 452
            ...|:.|.|:.......|    ...:...|::.|:  |::.|.:......:........:.....
Yeast   393 KFEDIDPYSVSYTWDKQVDDEDRLEVFPANSSYPS--TKLITLHRTGDFSMKAVYTHPSKLPKGT 455

  Fly   453 NNSLGKFELSAIP-PAPRGVPQVEVTFDIDANG---ILNVTALEKSTGKE--------------- 498
            :.::.|:..:.:. |..:....|:|....|.:|   |.|....|..|.:|
Yeast   456 STTIAKWSFTGVKVPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVPLPEDAPEDAEPQ 520

  Fly   499 -NRITITNDKG---------RLSKEDIERMVNDAEAYRQADEQQRDRINAKNQLESYCFQLRSTL 553
             ..:|.|..|.         .|:..::..::......|..|:...:..:.||.||.|.:.||:.|
Yeast   521 FKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETEDRKNALEEYIYTLRAKL 585

  Fly   554 DDEHLSSRFSPADRETIQQRSSETIAWL--------DANQLAERQEF---------------EHK 595
            |||: |...|.|::|.::...:.|..||        .|..:|:.:|.               |.|
Yeast   586 DDEY-SDFASDAEKEKLKNMLATTENWLYGDGDDSTKAKYIAKYEELASLGNIIRGRYLAKEEEK 649

  Fly   596 QQEL 599
            :|.|
Yeast   650 RQAL 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	182/654 (28%)
SSE2	NP_009728.1	ASKHA_ATPase-like	5..390	CDD:483947	131/386 (34%)