Protein Alignment Hsc70-1 and HSPA13

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_008879.3
• Gene: HSPA13 / 6782
• HGNCID: 11375
• Length: 471
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 162/424 - (38%)
• Similarity: 245/424 - (57%)
• Gaps: 50/424 - (11%)

  Fly     1 MPKLPAVGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNP 63
            :|....:||||||||..||||  ..|||::|.::.|:.:.||.|:||:::..:|..:......||
Human    28 LPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNP 92

  Fly    64 NNTIFDAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMR 128
            .|||:||||.||:.|....:::::..:||:|..:||.....|. ..|..:..||.|.|.:|.|::
Human    93 QNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLLLKLK 156

  Fly   129 ETAEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSER 193
            |.||||||..|.:||::|||.|:..||.:|.:|..:|||.:||:||||||||:||||.|....
Human   157 EMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVF-- 219

  Fly   194 NVLIFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKR 258
            :||:.||||||.|||:|..:.|:|..:|.:|:..|||:||:.||:.:..::..:.: ..:...|.
Human   220 HVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTY-GFVPSRKE 283

  Fly   259 ALRRLRTACERAK--RTLSSSTQASIEI-------------------DSLFEGVD---------- 292
            .:.|||.|.|..|  .||..|.|.|:.:                   |.|....|
Human   284 EIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRG 348

  Fly   293 ------------FYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMDKGQIHDIVLVGGSTRIPK 345
                        |.|.::|..|:.||.|||:..:.|:.:.|::..::|.:|.::||||||||||:
Human   349 LSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPR 413

  Fly   346 VQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAI 379
            :::::|:|| ||:.|.|::||.||..|.|:||.|
Human   414 IRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	162/424 (38%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	161/419 (38%)
HSPA13	NP_008879.3	HSPA13-like_NBD	12..463	CDD:212679	162/424 (38%)
		PRK13930	32..442	CDD:237564	157/414 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..352		3/36 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820