Protein Alignment Hsc70-1 and hspa14

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001038541.1
• Gene: hspa14 / 565232
• ZFINID: ZDB-GENE-041210-73
• Length: 504
• Species: Danio rerio
• Alignment Length: 514
• Identity: 178/514 - (34%)
• Similarity: 290/514 - (56%)
• Gaps: 31/514 - (6%)

  Fly     4 LPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIF 68
            :.|:|:..|.|.:||.||:.|:.:::|||.|:|.||:.||:.::|:::|.|||.....|..||:.
Zfish     1 MAAIGVHFGYTCACVAVFKDGRADVVANDAGDRVTPAVVAYRDTEQIVGIAAKQGRIRNAANTVV 65

  Fly    69 DAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEA 133
            ..|:::|||:||...|:..:.....|..::|.||..::.....|...||:|:.::..||:|||::
Zfish    66 KVKQILGRRYDDPDAQAHKEESKCIVVNKSGLPRYEIDTGETTKYVSPEDVAKLIFHKMKETAQS 130

  Fly   134 YLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQG-TSERNVLI 197
            .||..|.|||:|||..|::.|:.|.:.|...||.||||:|:||:||.:||.:.:.. ..:.:||:
Zfish   131 ALGSDVKDAVITVPFEFDEMQKNALRQAAESAGFNVLRLIHEPSAALLAYDIGQDSPLGKSHVLV 195

  Fly   198 FDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRR 262
            :.|||.:..|:||.:..|::.|.||..|...|||.|...|..|...||::..|:|:..|.||:.:
Zfish   196 YKLGGTSLSVTVLEVNSGVYRVLATQTDHQTGGESFTQELAQHLAAEFKKTFKQDVSGNARAMMK 260

  Fly   263 LRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMD 327
            |..:.:.||.|||:...|:..:|||::|:||..:|:|||||.:...||...::|:...|....:.
Zfish   261 LMNSADVAKHTLSTLGSANCFVDSLYDGMDFECNVSRARFELICSSLFNKCIQPIKSLLEQVNLS 325

  Fly   328 KGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAV-QDL 391
            ...::.:||.|||.||||:|::::|.|...||..||.|||.:..|||:||.||.|..|.|: :|.
Zfish   326 TSDVNKVVLSGGSARIPKLQQMIRDLFPDVELLNSIPPDEVIPVGAAMQAGILVGKDSLALGEDS 390

  Fly   392 LLLD--VTPLSL------GIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPG----VLIQVFE 444
            :.:|  .:.::|      |:|    |.|.|....|.:|.::....     ..||    |.:|:|:
Zfish   391 ITVDCCASDITLKEVDDSGLE----VFTVLFPSGTPLPARRQHTL-----QGPGSLSSVRLQLFQ 446

  Fly   445 GERAMTRDNNSLGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITI 503
            .::       .:.:..|..:.|... :..|.....:..:|.|:||..|:|:|:...|||
Zfish   447 AQQ-------PIAQIVLGDLEPKEE-LHDVVTVLTMKRDGSLHVTCTEQSSGRSEAITI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	178/514 (35%)
hspa14	NP_001038541.1	ASKHA_NBD_HSP70_HSPA14	2..378	CDD:466836	145/375 (39%)