Protein Alignment Hsc70-1 and hspa12a.2

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001429582.1
• Gene: hspa12a.2 / 559237
• ZFINID: ZDB-GENE-061009-20
• Length: 571
• Species: Danio rerio
• Alignment Length: 608
• Identity: 133/608 - (21%)
• Similarity: 234/608 - (38%)
• Gaps: 164/608 - (26%)

  Fly     7 VGIDLGTTYSCVGVF----QHGKVEIIAN---DQGNRT--TPSYVAFTESE--RLIGDAAKNQVA 60
            :.||.||:||...:.    |..:..:|.|   |.|..|  ||:.:.|.|.|  :..|
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESILIPNWGVDYGYNTFKTPTCILFDEHETFQKFG-------- 64

  Fly    61 MNPNNTIFDAKRLIGRRFDDATVQSD------MKHWPFEVF-----------AENGKPRIRVEYK 108
                   :||.....|    :||:|.      .:|:..|::           |:||
Zfish    65 -------YDAMMTYTR----STVKSQARKSFLFEHFKMELYDKEIHRDLMITAKNG--------- 109

  Fly   109 GERKSF--YPEEVSSM---VLTKMRE--TAEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAG 166
            |:.|:.  :.|.:..:   .|.|::|  |.:.::...|| .|:||||.:|.:.:|..::|...||
Zfish   110 GQMKALTVFSESLRYLKDHALEKVKENPTGKTFIASDVT-WVLTVPAIWNAAAKQFMREAAIEAG 173

  Fly   167 LNV------LRIINEPTAAAI------AYGL-----------DKQGTSERNVLIFDLGGGTFDVS 208
            |.:      |....||.||:|      :.|.           .|.||   ..::.|.||||.|::
Zfish   174 LVIESEPERLVFALEPEAASIYCKHLPSEGYISEEACRDTLEQKPGT---QYMVVDCGGGTIDIT 235

  Fly   209 V-LTIEDG-IFEVKATAGDTHLGG------------EDFDNRLVNHFVQEFQR---KHKKDLGQN 256
            | ..:||| :.|:.|.:|: .:||            |.|..::.|.|.|:|..   |.|.|:...
Zfish   236 VHEVVEDGKLKELNAASGN-DMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALA 299

  Fly   257 KRALRRLRTACERAKRTLSSSTQASIEIDSLFEGV------DFYTSVTRARFEELNGDLFRGTME 315
            |...:.:...|....:.|:...:|   |:|.||||      :....:...:.:....:..:.|.|
Zfish   300 KSCDQLVLIQCPVTLQELAKKEKA---IESYFEGVEGAEWDEGSIIIKEDKLQSFFDESLKTTAE 361

  Fly   316 PVAKALRDAKMDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPD-------------- 366
            .:.|...:.:::   |..::||||......:::.|::.|:..::...:.|.
Zfish   362 KLEKITSNPELN---IEYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQP 423

  Fly   367 -------EAVAYGAAVQA---AILHGDKSEAVQDLLLLDVTPLSLGIETAGGVMTTLIKRNTTIP 421
                   .|:.||..:.|   .:||.|||..|.          |.|.........|.:::..::.
Zfish   424 KVVKSRMSALTYGIRIDAPFDKVLHKDKSNYVN----------SEGQTYCDVCFETFVRKGESVN 478

  Fly   422 TKQTQ--IFTTYADNQPGVLIQVFEGERAMTR--DN---NSLGKFELSAIPPAPRGVPQVEVTFD 479
            ..:.:  .|.....||...:.|.|.......:  |.   ..:|.||: .:|....|:.: |:..:
Zfish   479 CDEVRQFFFNPSHTNQTSAIFQFFSTNEKQVQFIDEPGVEPVGFFEV-GMPKTDGGLSR-EIKLE 541

  Fly   480 IDANGI-LNVTALEKSTGKENRI 501
            |..... :..||.:..:|:...:
Zfish   542 IKFGSTEMKATATDVDSGETTSV 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	133/608 (22%)
hspa12a.2	NP_001429582.1	None