Protein Alignment Hsc70-1 and hspa14

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001015780.1
• Gene: hspa14 / 548497
• XenbaseID: XB-GENE-5932856
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 171/512 - (33%)
• Similarity: 289/512 - (56%)
• Gaps: 20/512 - (3%)

  Fly     4 LPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIF 68
            :.|:|:.||.|.:||.|::.|:.:::|||.|:|.||:.|.|.|.|.::|.|||.....|..|||.
 Frog     1 MAAIGVHLGCTCACVAVYKDGRADVVANDAGDRVTPAVVGFLEKETIVGLAAKQSRVRNATNTIV 65

  Fly    69 DAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFY-PEEVSSMVLTKMRETAE 132
            ..|:::||.:.|...|..:......|..:.|||:..:: .||.:.|. .|:|:.::.:||:|||:
 Frog    66 KVKQILGRSYGDPHTQKHISESKCIVVEKVGKPKYEID-TGETQKFVSSEDVAKLIFSKMKETAQ 129

  Fly   133 AYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQG-TSERNVL 196
            :.||..|.|.|:|||..|.:||::|..:|...||.::||:|:||:||.:|||:.::. |.:.|||
 Frog   130 SALGSDVNDVVITVPFDFGESQKKALGEAATAAGFSILRMIHEPSAALLAYGIGQESPTGKSNVL 194

  Fly   197 IFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALR 261
            ::.|||.:..|:|:.:..||:.|.||:....:||..|...|..|...||||.:|:|:..|.||:.
 Frog   195 VYKLGGTSLSVTVIEVNSGIYRVLATSTYDDIGGICFTEALAQHLASEFQRTYKQDIRGNARAMM 259

  Fly   262 RLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKM 326
            :|..:.:.||..||:...::..:|||::|:||..:|:|||||.:...||...::|:.|.|.....
 Frog   260 KLMNSADVAKHALSTLGSSNCFVDSLYDGIDFDCNVSRARFELICSSLFNQCIDPIKKLLEQIGF 324

  Fly   327 DKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQ-D 390
            ....::.:||.|||.||||:|:|::|.|...|:..||.|||.:..|||:||.||.|.::.:.. |
 Frog   325 KANDVNQVVLCGGSARIPKLQQLIKDLFPEVEMLSSIPPDEVIPVGAAIQAGILIGKENLSTDLD 389

  Fly   391 LLLLDVTPLSLGI----ETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPG----VLIQVFE-GE 446
            .:.::.:...:.:    |:.....|.|:...|.:|.::..:.     ..||    |.::::| |.
 Frog   390 TITIECSASDILVKETDESGDNKFTVLLPSGTPLPARRQHVL-----QAPGHISSVCLELYESGG 449

  Fly   447 RAMTRDNNSLGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITI 503
            ::..  .:...:..|..:.....||..:.....:..:|.|::|..:|.:||...||:
 Frog   450 KSPV--ESKFAQIVLKDLQKKASGVHDILTVLTMKRDGSLHITCTDKDSGKSEMITV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	171/512 (33%)
hspa14	NP_001015780.1	ASKHA_NBD_HSP70_HSPA14	2..378	CDD:466836	146/376 (39%)