Protein Alignment Hsc70-1 and Hsp70Bc

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 466/642 - (72%)
• Similarity: 546/642 - (85%)
• Gaps: 5/642 - (0%)

  Fly     4 LPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIF 68
            :||:|||||||||||||:||||||||||||||||||||||||:|||||||.|||||||||.||:|
  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65

  Fly    69 DAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEA 133
            ||||||||::||..:..|||||||:|.::.|||:|.||||||.|.|.|||:||||||||:|||||
  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130

  Fly   134 YLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIF 198
            |||.::||||:||||||||||||||||||.|||||||||||||||||:||||||....|||||||
  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 195

  Fly   199 DLGGGTFDVSVLTIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRR 262
            ||||||||||:|||::| :|||::|||||||||||||||||.|..:||:||:||||..|.|||||
  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRR 260

  Fly   263 LRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMD 327
            ||||.|||||||||||:|:||||:||||.||||.|:|||||||..||||.|::||.|||.|||||
  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMD 325

  Fly   328 KGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDLL 392
            ||||||||||||||||||||.|||:||:||.||.|||||||||||||||||||.||:|..:||:|
  Fly   326 KGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVL 390

  Fly   393 LLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSLG 457
            |:||.||||||||||||||.||:||..||.|||:.|:||:||||||.|||:|||||||:|||:||
  Fly   391 LVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALG 455

  Fly   458 KFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVNDA 522
            .|:||.||||||||||:|||||:||||||||:|.|.||||...|||.|||||||:.:|:||||:|
  Fly   456 TFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEA 520

  Fly   523 EAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQLA 587
            |.|...||:.|.||.::|.||||.|.::.:: ::..:.:...||:.::..:.:|||.|||:|..|
  Fly   521 EKYADEDEKHRQRITSRNALESYVFNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTA 584

  Fly   588 ERQEFEHKQQELERICSPIITRLY-QGAGMAPPPTAG-GSNPGATGG-SGPTIEEVD 641
            |::||:||.:||.|.||||:|::: ||||.|..|.|. |...|..|| ||||:||||
  Fly   585 EKEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGFGGYSGPTVEEVD 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	464/640 (73%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	305/375 (81%)
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	464/639 (73%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	305/375 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440310
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		mtm9161
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.740