Protein Alignment Hsc70-1 and Hsp70Ab

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 465/643 - (72%)
• Similarity: 542/643 - (84%)
• Gaps: 6/643 - (0%)

  Fly     4 LPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIF 68
            :||:|||||||||||||:||||||||||||||||||||||||:|||||||.|||||||||.||:|
  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65

  Fly    69 DAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEA 133
            ||||||||::||..:..|||||||:|.::.|||:|.||||||.|.|.|||:||||||||:|||||
  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130

  Fly   134 YLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIF 198
            |||.::||||:||||||||||||||||||.|||||||||||||||||:||||||....|||||||
  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 195

  Fly   199 DLGGGTFDVSVLTIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRR 262
            ||||||||||:|||::| :|||::|||||||||||||||||.|...||:||:||||..|.|||||
  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRR 260

  Fly   263 LRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMD 327
            ||||.|||||||||||:|:||||:||||.||||.|:|||||||..||||.|::||.|||.|||||
  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMD 325

  Fly   328 KGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDLL 392
            ||||||||||||||||||||.||||||:||.||.|||||||||||||||||||.||:|..:||:|
  Fly   326 KGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVL 390

  Fly   393 LLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSLG 457
            |:||.||||||||||||||.||:||..||.|||:.|:|||||||||.|||:|||||||:|||:||
  Fly   391 LVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALG 455

  Fly   458 KFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVNDA 522
            .|:||.||||||||||:|||||:||||||||:|.|.||||...|||.|||||||:.:|:||||:|
  Fly   456 TFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEA 520

  Fly   523 EAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQLA 587
            |.|...||:.|.||.::|.||||.|.::..: ::..:.:...||:.::..:.::||.|||:|..|
  Fly   521 EKYADEDEKHRQRITSRNALESYVFNVKQAV-EQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTA 584

  Fly   588 ERQEFEHKQQELERICSPIITRLYQ---GAGMAPPPTAGGSNPGATGG-SGPTIEEVD 641
            |::||:||.:||.|.||||:|:::|   |||...|....|...|..|| ||||:||||
  Fly   585 EKEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAGGFGGYSGPTVEEVD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	463/641 (72%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	306/375 (82%)
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	463/640 (72%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	306/375 (82%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440308
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.750