Protein Alignment Hsc70-1 and Hsc70Cb

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Alignment Length: 699
• Identity: 201/699 - (28%)
• Similarity: 334/699 - (47%)
• Gaps: 107/699 - (15%)

  Fly     4 LPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIF 68
            :..:|||.|.....|...:.|.:|.:|||...|.|||:|||...:|:||.|||||...|..||:.
  Fly     1 MSVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVG 65

  Fly    69 DAKRLIGRRFDDATVQSDMKHWPFEVFAE-NGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAE 132
            ..|||:||:|:|..||.::...|..|.|. :|...|:|.|.||.:.|.||::::|:.||::||:.
  Fly    66 GFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSA 130

  Fly   133 AYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSE---RN 194
            |.:...|.|.|:..|.:|.:::|:|..||..||||||||::||.||.|:|||..|....|   ||
  Fly   131 AAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRN 195

  Fly   195 VLIFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRA 259
            |:..|.|..:...|......|..::.|:..| .:||.|.|..|.::|.:|||.::|.:...|.||
  Fly   196 VIFVDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNARA 259

  Fly   260 LRRLRTACERAKRTLS-SSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRD 323
            ..||.|..|:.|:.:| :||:..:.|:...:.:|..:|:.|::.|||...:.:...:...:.|.:
  Fly   260 NLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAE 324

  Fly   324 AKMDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAV 388
            :|:....||.:.:||||:|||.|::|::..|| |..:.::|.||||:.|||:|.||:  ..:..|
  Fly   325 SKLQLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIM--SPAVRV 386

  Fly   389 QDLLLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTY---------ADNQPGVL-IQVF 443
            ::..:.|:...::.:         |.....:....:.:||..|         ..|:.|.. :.:.
  Fly   387 REFGVTDIQNYAVKV---------LWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGPFNVSIV 442

  Fly   444 EGERAMTRDNNSLGKFELSAIPPAPRGVPQ-VEVTFDIDANGIL---NVTALEKSTGKE------ 498
            .|::....| .::|.:::..:.|..||..| |::...|:.|||:   :.|.:||...:|
  Fly   443 YGQQVPYPD-QTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAE 506

  Fly   499 ---------------------------------NRITITN------------------DKGRLSK 512
                                             |..|.::                  ||.:.:.
  Fly   507 QAASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKAS 571

  Fly   513 EDIERMVN---------DAEAYRQA-------DEQQRDRINAKNQLESYCFQLRSTLDDEHLSSR 561
            :..|..:.         |...|.|.       |:::.:||:|||.||.:.:.:|:.|........
  Fly   572 KATELPLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERY 636

  Fly   562 FSPADRETIQQRSSETIAWL-DANQLAERQEFEHKQQELERICSPIITR 609
            ...|:||.|..:.::...|| :..:..||..:..:.|.|.:...||..|
  Fly   637 VVEAEREKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLR 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	201/699 (29%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	146/379 (39%)
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	146/382 (38%)
		HSP70	3..682	CDD:278441	198/692 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464204
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740