Protein Alignment Hsc70-1 and Hsc70-5

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 304/633 - (48%)
• Similarity: 413/633 - (65%)
• Gaps: 19/633 - (3%)

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-ESERLIGDAAKNQVAMNPNNTIFDA 70
            :|||||||.||:.|.:..:.::|.|.:|.|||||:|||| :.|||:|..||.|...|..||.:..
  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119

  Fly    71 KRLIGRRFDDATVQSDMKHWPFEVF-AENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAY 134
            ||||||||||..|:.|:.:..::|. |.||...:.   ..:.|.:.|.::.:.:|.||:||||||
  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKETAEAY 181

  Fly   135 LGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIFD 199
            |...|.:|||||||||||||||||||||.||||||||:||||||||:|||:||  |.::.:.::|
  Fly   182 LNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDK--TEDKIIAVYD 244

  Fly   200 LGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRRLR 264
            |||||||:|:|.|:.|:||||:|.|||.||||||||.:||..|.||::....|:.::..|::||:
  Fly   245 LGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLK 309

  Fly   265 TACERAKRTLSSSTQASIEIDSLFEGV----DFYTSVTRARFEELNGDLFRGTMEPVAKALRDAK 325
            .|.|:||..||||.|..|.:..|....    .....:||::.|.|.|||.:.|::|..|||.||:
  Fly   310 EAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSDAE 374

  Fly   326 MDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQD 390
            :.|.:|.:::||||.||:||||..:|:.| |::.::|:|||||||.|||||..:|.||    |.|
  Fly   375 VSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD----VTD 434

  Fly   391 LLLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNS 455
            :||||||||||||||.|||.|.||.||||||||::|:|:|.:|.|..|.|:|.:|||.|..||..
  Fly   435 VLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNKL 499

  Fly   456 LGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVN 520
            ||.|.|..||||||||||:||.||||||||::|:|.:|.||||.:|.| ...|.|||::||.|:.
  Fly   500 LGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSSGGLSKDEIENMIK 563

  Fly   521 DAEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQ 585
            .||.|..||:|:|:.|...||.||......:.:  |...|:....:.|.:::..::....|...:
  Fly   564 KAEEYATADKQKRELIEIVNQGESIVHDTETKM--EEFKSQLPAEECEKLKKEIADLRTLLANKE 626

  Fly   586 LAERQEFEHKQQELERICSPIITRLYQGAGMAPPPTAGGSNPGATGGS 633
            .|:.:|.......|::....:....|:.........||..:..::..|
  Fly   627 TADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSS 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	304/633 (48%)
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	303/623 (49%)