Protein Alignment Hsc70-1 and Hspa12a

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_017444569.1
• Gene: Hspa12a / 307997
• RGDID: 1305531
• Length: 691
• Species: Rattus norvegicus
• Alignment Length: 665
• Identity: 144/665 - (21%)
• Similarity: 233/665 - (35%)
• Gaps: 215/665 - (32%)

  Fly     4 LPAVGIDLGTTYS-----------CVGVFQHGKVEIIANDQG--NRTTPSYVAFTESERL--IGD 53
            |..|.||.|||.|           |:.|.:..:    ..|.|  |:.||:.:..|...:.  .|.
  Rat    72 LVVVAIDFGTTSSGYAYSFTKEPECIHVMRRWE----GGDPGVSNQKTPTTILLTPERKFHSFGY 132

  Fly    54 AAKN-QVAMNPNNTIFDAKR-LIGRRF-------DDATVQSDMKHWPFEVFAENGKPRIRVEYKG 109
            ||:: ...::||    :||: |...:|       .|.|:.:|:.       |.|||....:|...
  Rat   133 AARDFYHDLDPN----EAKQWLYLEKFKMKLHTTGDLTMDTDLT-------AANGKKVKALEIFT 186

  Fly   110 ERKSFYPEEVSSMVLTKMRETAEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGL------N 168
            ....::.|:    .|.::.:.|.:....:....|:||||.:....:|..::|...|||      .
  Rat   187 YALQYFKEQ----ALKELSDQAGSDFENSDVRWVITVPAIWKQPAKQFMREAAYQAGLASPENSE 247

  Fly   169 VLRIINEPTAA------------------AIAYGLDKQGT-----------SERN---------- 194
            .|.|..||.||                  |:..|.....|           ..||
  Rat   248 QLIIALEPEAASIYCRKLRLHQMIELSSKAVVNGYSASDTVGAGFAQAKEHVRRNRQSRTFLVEN 312

  Fly   195 --------------VLIFDLGGGTFDVSV--LTIEDGIFE--VKATAGDTHLGGEDFD-NRLV-- 238
                          .::.|.||||.|::|  :.:.:|..:  .|||.|.....|.|:: .:|:
  Rat   313 VIGEIWSELEEGDKYVVVDSGGGTVDLTVHQIRLPEGHLKELYKATGGPYGSLGVDYEFEKLLCK 377

  Fly   239 ---NHFVQEFQRKHKKDLGQNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYT----- 295
               ..|:::|:.|       ...|...|..|.|..||..:......:.|...|..:|:|.
  Rat   378 IFGEDFIEQFKIK-------RPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGH 435

  Fly   296 SVTRARFEELNGD-------------------LFRGTMEPVAKALRD--AKMDKGQIHDIVLVGG 339
            ||..| ..:.|.|                   ||:.|::.:.:.|||  .|.:...:..:.||||
  Rat   436 SVEHA-LRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDSIIEHLRDLFQKPEVSTVKFLFLVGG 499

  Fly   340 STRIPKVQRLLQDFFNGK-------ELNKSI-------NPDEAV--------AYGAAVQAAILHG 382
            ....|.:|:.:|..|..|       ::..:|       ..|.||        .||..|....:.|
  Rat   500 FAEAPLLQQAVQAAFGDKCRIIIPQDVGLTILKGAVLFGLDPAVIKVRRSPLTYGVGVLNRYVEG 564

  Fly   383 DKSEAVQDLLLLDVTP---------LSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGV 438
              ....:.||:.|.|.         :|.....|.|   .|:||:.| |.|.:|:.         :
  Rat   565 --KHPPEKLLVKDGTRWCTDVFDKFISADQSVALG---ELVKRSYT-PAKPSQLV---------I 614

  Fly   439 LIQVFEGERAMTRDNNSL---------GKFEL------SAIPPAPRGVPQVEVTFDIDANGILNV 488
            :|.::..|    .|:.|.         |...|      .|..||.|.:..:....|.:    :..
  Rat   615 IINIYSSE----NDDVSFITDPGVKKCGTLRLDLTGTSGAAVPARREIQTLMQFGDTE----IKA 671

  Fly   489 TALEKSTGKENRITI 503
            ||::.:|.|..::.|
  Rat   672 TAVDIATSKSVKVGI 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	144/665 (22%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	112/515 (22%)
Hspa12a	XP_017444569.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810