Protein Alignment Hsc70-1 and hsp70.3

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_571472.2
• Gene: hsp70.3 / 30671
• ZFINID: ZDB-GENE-110713-1
• Length: 643
• Species: Danio rerio
• Alignment Length: 642
• Identity: 501/642 - (78%)
• Similarity: 578/642 - (90%)
• Gaps: 4/642 - (0%)

  Fly     2 PKLPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNT 66
            ||..|:||||||||||||||||||||||||||||||||||||||::|||||||||||||||||||
Zfish     4 PKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNT 68

  Fly    67 IFDAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETA 131
            :|||||||||||||..||||||||.|:|.::.|||::.||:|||.|:|.|||:|||||.||:|.|
Zfish    69 VFDAKRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIA 133

  Fly   132 EAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVL 196
            |||||..||:||:||||||||||||||||||.||||||||||||||||||||||||..:||||||
Zfish   134 EAYLGQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVL 198

  Fly   197 IFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALR 261
            ||||||||||||:|||||||||||||||||||||||||||:|||||:||:||||||:.|||||||
Zfish   199 IFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALR 263

  Fly   262 RLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKM 326
            ||||||||||||||||:|||||||||:||:|||||:||||||||..||||||::||.||||||||
Zfish   264 RLRTACERAKRTLSSSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALRDAKM 328

  Fly   327 DKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDL 391
            ||.||||||||||||||||:|:||||||||:|||||||||||||||||||||||.||.|..||||
Zfish   329 DKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQDL 393

  Fly   392 LLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSL 456
            |||||.||||||||||||||.||||||||||||||.||||:||||||||||||||||||:|||.|
Zfish   394 LLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLL 458

  Fly   457 GKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVND 521
            |||||:.||||||||||:||||||||||||||:|.:|||||:|:|||||||||||||:|||||.:
Zfish   459 GKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNKITITNDKGRLSKEEIERMVQE 523

  Fly   522 AEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQL 586
            |:.|:..|:.||::|:|||.||||.|.::::::|::|..:.|..|::.:.::.:|.::||:.|||
Zfish   524 ADKYKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRVIEKCNEAVSWLENNQL 588

  Fly   587 AERQEFEHKQQELERICSPIITRLYQGAGMAPPPTAGGSNPGATGGS--GPTIEEVD 641
            |:::|:||:.:|||::|:|:|::|||| || |....|....||:|.|  ||||||||
Zfish   589 ADKEEYEHQLKELEKVCNPVISKLYQG-GM-PAGGCGAQARGASGASAQGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	499/640 (78%)
hsp70.3	NP_571472.2	PTZ00009	5..643	CDD:240227	498/639 (78%)