Protein Alignment Hsc70-1 and hsp-3

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001370435.1
• Gene: hsp-3 / 180880
• WormBaseID: WBGene00002007
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 379/628 - (60%)
• Similarity: 500/628 - (79%)
• Gaps: 12/628 - (1%)

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT--ESERLIGDAAKNQVAMNPNNTIFD 69
            :|||||||||||||:::|:|||||||||||.|||||||:  :.:||||||||||:.:||.|||||
 Worm    36 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFD 100

  Fly    70 AKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAY 134
            |||||||.::|.|||:|:|||||:|..::.||.:.|:...:.|.|.|||||:|||.||:|.||:|
 Worm   101 AKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESY 165

  Fly   135 LGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIFD 199
            ||..|.:|||||||||||:|||||||||.||||||:|||||||||||||||||: ..|||:|:||
 Worm   166 LGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKK-DGERNILVFD 229

  Fly   200 LGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRRLR 264
            |||||||||:|||::|:|||.||.|||||||||||.|::.:|::.:::|..|||.::|||:::||
 Worm   230 LGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLR 294

  Fly   265 TACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMDKG 329
            ...|:|||.||:..|..:||:|||:|.||..::|||:|||||.||||.|::||.|.|.|:.:.|.
 Worm   295 REVEKAKRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKD 359

  Fly   330 QIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDLLLL 394
            .:|:||||||||||||||:|:::||||||.::.||||||||||||||..::.|:  |...:::||
 Worm   360 DVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGE--EDTGEIVLL 422

  Fly   395 DVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSLGKF 459
            ||.||::||||.|||||.||.|||.||||::|:|:|.|||||.|.||||||||.||:||:.||||
 Worm   423 DVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKF 487

  Fly   460 ELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVNDAEA 524
            :|:.:|||||||||:||||:||.||||:|||.:|.||.:|:||||||:.|||.||||||:||||.
 Worm   488 DLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEK 552

  Fly   525 YRQADEQQRDRINAKNQLESYCFQLRSTLDD-EHLSSRFSPADRETIQQRSSETIAWLDANQLAE 588
            :.:.|::.:|:..|:|:||||.:.|::.::| |.|..:....|::||::...|.|:||.:|..|.
 Worm   553 FAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGSNAEAS 617

  Fly   589 RQEFEHKQQELERICSPIITRLYQGAGMAPPPTAGGSNPGATG 631
            .:|.:.::::||....||:::||:.||      |||......|
 Worm   618 AEELKEQKKDLESKVQPIVSKLYKDAG------AGGEEAPEEG 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	379/628 (60%)
hsp-3	NP_001370435.1	PTZ00009	32..648	CDD:240227	377/620 (61%)