Protein Alignment Hsc70-1 and hsp-1

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_503068.1
• Gene: hsp-1 / 178507
• WormBaseID: WBGene00002005
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 513/643 - (79%)
• Similarity: 571/643 - (88%)
• Gaps: 5/643 - (0%)

  Fly     1 MPKLPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNN 65
            |.|..||||||||||||||||.|||||||||||||||||||||||::||||||||||||||||:|
 Worm     1 MSKHNAVGIDLGTTYSCVGVFMHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPHN 65

  Fly    66 TIFDAKRLIGRRFDDATVQSDMKHWPFEVF-AENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRE 129
            |:|||||||||:|||..||||||||||:|. ||..||:::||||||.|.|.|||:|||||.||:|
 Worm    66 TVFDAKRLIGRKFDDPAVQSDMKHWPFKVISAEGAKPKVQVEYKGENKIFTPEEISSMVLLKMKE 130

  Fly   130 TAEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERN 194
            ||||:||.||.|||||||||||||||||||||||||||||||||||||||||||||||:|..|||
 Worm   131 TAEAFLGTTVKDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKGHGERN 195

  Fly   195 VLIFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRA 259
            ||||||||||||||:|||||||||||:|||||||||||||||:||||..||:|||||||..|.||
 Worm   196 VLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFCAEFKRKHKKDLASNPRA 260

  Fly   260 LRRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDA 324
            ||||||||||||||||||:||||||||||||:||||::||||||||..||||.||:||.|:||||
 Worm   261 LRRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTNITRARFEELCADLFRSTMDPVEKSLRDA 325

  Fly   325 KMDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQ 389
            ||||.|:||||||||||||||||:||.|.|:|||||||||||||||||||||||||.||||||||
 Worm   326 KMDKSQVHDIVLVGGSTRIPKVQKLLSDLFSGKELNKSINPDEAVAYGAAVQAAILSGDKSEAVQ 390

  Fly   390 DLLLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNN 454
            |||||||.||||||||||||||.|||||||||||..|.||||:||||||||||:|||||||:|||
 Worm   391 DLLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKTAQTFTTYSDNQPGVLIQVYEGERAMTKDNN 455

  Fly   455 SLGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMV 519
            .|||||||.||||||||||:||||||||||||||:|.:|||||:|:||||||||||||:||||||
 Worm   456 LLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSATDKSTGKQNKITITNDKGRLSKDDIERMV 520

  Fly   520 NDAEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDAN 584
            |:||.|:..||.|:|||.|||.||||.|.|:.|::||.|..:.||.|::.|:.:..|.:.|||:|
 Worm   521 NEAEKYKADDEAQKDRIGAKNGLESYAFNLKQTIEDEKLKDKISPEDKKKIEDKCDEILKWLDSN 585

  Fly   585 QLAERQEFEHKQQELERICSPIITRLYQGAGMAPPPTAGGSNPGATGGS-GPTIEEVD 641
            |.||::||||:|::||.:.:|||::|||.||.|||..|.|   ||.||: ||||||||
 Worm   586 QTAEKEEFEHQQKDLEGLANPIISKLYQSAGGAPPGAAPG---GAAGGAGGPTIEEVD 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	511/641 (80%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	322/375 (86%)
hsp-1	NP_503068.1	PTZ00009	1..614	CDD:240227	493/612 (81%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	322/375 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156866
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68524
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S49
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		otm14593
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.610