Protein Alignment Hsc70-1 and hsp-4

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001370395.1
• Gene: hsp-4 / 174203
• WormBaseID: WBGene00002008
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 612
• Identity: 367/612 - (59%)
• Similarity: 486/612 - (79%)
• Gaps: 6/612 - (0%)

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT--ESERLIGDAAKNQVAMNPNNTIFD 69
            :||||||||||||||::|:|||||||||||.|||||||:  :.|||||||||||:.:||.|||||
 Worm    33 IGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDQGERLIGDAAKNQLTINPENTIFD 97

  Fly    70 AKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAY 134
            |||||||.:::.|||.|:|||||::..::.||.:.|:...|.|.|.|||||:||||||::.||:|
 Worm    98 AKRLIGRFYNEKTVQQDIKHWPFKIVDKSNKPNVEVKVGSETKQFTPEEVSAMVLTKMKQIAESY 162

  Fly   135 LGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIFD 199
            ||..|.:|||||||||||:|:|||||||:||||||:|||||||||||||||||: ..|||:|:||
 Worm   163 LGHEVKNAVVTVPAYFNDAQKQATKDAGSIAGLNVVRIINEPTAAAIAYGLDKK-DGERNILVFD 226

  Fly   200 LGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRRLR 264
            |||||||||:|||:.|:|||.||.|||||||||||.|::.:|::.:::|..|||.::.||:::||
 Worm   227 LGGGTFDVSLLTIDSGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDNRAVQKLR 291

  Fly   265 TACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMDKG 329
            ...|:|||.||:..|..|||:|||:|.||..::|||:|||||.||||.|::||.|.|.||.|.|.
 Worm   292 REVEKAKRALSTQHQTKIEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDADMKKT 356

  Fly   330 QIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDLLLL 394
            .:|:||||||||||||||:|::|:|||||.::.|||||||||||||||.::.|  .|...|::||
 Worm   357 DVHEIVLVGGSTRIPKVQQLIKDYFNGKEPSRGINPDEAVAYGAAVQAGVIGG--VENTGDVVLL 419

  Fly   395 DVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSLGKF 459
            ||.||:|||||.|||||.||.|||.||||::|:|:|.||:|..|.|.::||||.|..||:.||.|
 Worm   420 DVNPLTLGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADSQSAVSIVIYEGERPMVMDNHKLGNF 484

  Fly   460 ELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVNDAEA 524
            :::.||||||||||:||||:||.||||:|:|.:|.||.:|::|||||..|||.||||||:|||:.
 Worm   485 DVTGIPPAPRGVPQIEVTFEIDVNGILHVSAEDKGTGNKNKLTITNDHNRLSPEDIERMINDADK 549

  Fly   525 YRQADEQQRDRINAKNQLESYCFQLRSTL-DDEHLSSRFSPADRETIQQRSSETIAWLDANQLAE 588
            :...|:.|::::.::|:||:|.:|:::.: |.|.|..:.:..|:.:|:......|.||.:||.|.
 Worm   550 FAADDQAQKEKVESRNELEAYAYQMKTQIADKEKLGGKLTDEDKVSIESAVERAIEWLGSNQDAS 614

  Fly   589 RQEFEHKQQELERICSPIITRLYQGAG 615
            .:|.:.:::|||.:..||:::||...|
 Worm   615 TEENKEQKKELESVVQPIVSKLYSAGG 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	367/612 (60%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	251/375 (67%)
hsp-4	NP_001370395.1	PTZ00009	33..643	CDD:240227	367/612 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730