Protein Alignment Hsc70-1 and hspa12a

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_002941887.2
• Gene: hspa12a / 100489323
• XenbaseID: XB-GENE-959285
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 664
• Identity: 132/664 - (19%)
• Similarity: 219/664 - (32%)
• Gaps: 226/664 - (34%)

  Fly     7 VGIDLGTTYS-----------CVGVFQHGKVEIIANDQG--NRTTPSYVAFTESERLIGDAAKNQ 58
            |.||.|||.|           |:.:.:..:    ..|.|  |:.||:.:......:
 Frog    56 VAIDFGTTSSGYAYSFSKEPECIHIMRRWE----GGDPGVSNQKTPTTMLLMPDRK--------- 107

  Fly    59 VAMNPNNTIFDAKRLIGRRFDDATVQSDMKHWPF------------------EVFAENGKPRIRV 105
                     |.:.....|.|......|:.|||.:                  |:.|.|||....:
 Frog   108 ---------FHSFGFAARDFYHDLDPSESKHWLYFEKFKMKLHSSTDLTMETELTAANGKRVKAL 163

  Fly   106 EYKGERKSFYPEEVSSMVLTKMRETAEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGL--- 167
            |.......::.|:    .|.::.:.|.:.:.......|:||||.:....:|..:.|...||:
 Frog   164 EIFAYALQYFKEQ----ALKELSDQAGSEMDSAEVRWVITVPAIWKQPAKQFMRQAAYKAGMATP 224

  Fly   168 ---NVLRIINEPTAAAI---------------------------AYGLDKQGTSERNVL------ 196
               ..|.|..||..|:|                           |..|.::....|..|
 Frog   225 ENPEQLIIALEPEGASIYCRKLRLHQMIDLSSKAAINGISPTDPAKDLARRNRQSRTFLVENVIG 289

  Fly   197 -------------IFDLGGGTFDVSV--LTIEDGIFE--VKATAGDTHLGGEDFD-NRLV----- 238
                         :.|.||||.|::|  :.:.:|..:  .||:.|.....|.|:: .:|:
 Frog   290 ELWSELEEGDRYVVVDCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSLGVDYEFEKLLCKIFG 354

  Fly   239 NHFVQEFQRKHKKDLGQNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYT-----SVT 298
            :.|:..|:.|       ...|...|..|.|..||..:......:.|...|..:|:|.     ||.
 Frog   355 DDFIDTFKVK-------RPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSVE 412

  Fly   299 RARFE--------------ELNGD----LFRGTMEPVAKALRD--AKMDKGQIHDIVLVGGSTRI 343
            .|..:              .:|.|    ||:.|::|:.:.|.:  .|.:...:..:.||||....
 Frog   413 HALRKSNVDFVKWSSQGMLRMNPDAMNALFKPTIDPIIQHLTNLFQKPEVAGVKFLFLVGGFAES 477

  Fly   344 PKVQRLLQDFFNGKELNKSINPD-----------------------EAVAYGAAVQAAILHGDKS 385
            |.:|:.:|..| |.:....|..|                       ..:.||..|....:.|  .
 Frog   478 PLLQQAVQQAF-GDQCRVIIPHDVGLTILKGAVLFGLDPALIKVRRSPLTYGVGVLNRYVEG--K 539

  Fly   386 EAVQDLLLLDVT---------------PLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQ 435
            ...:.|||.|.|               .::|| ||        :||:.| |.||:|:.
 Frog   540 HPPEKLLLKDGTRWCTDVFDKFILADQSVALG-ET--------VKRSYT-PAKQSQLI------- 587

  Fly   436 PGVLIQVFEGERAMTRDNNSL--------GKFELSAIPPAPRGVP---QVEVTFDIDANGILNVT 489
              ::|.::..|:   .|.|.:        |...|....|....||   :::.........| ..|
 Frog   588 --IIIHIYSSEQ---DDANFITDKGVRKCGTLRLDLTGPESAPVPSRREIQTIMQFGDTEI-KAT 646

  Fly   490 ALEKSTGKENRITI 503
            |::.:|.|..:::|
 Frog   647 AVDVATSKNVKVSI 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	132/664 (20%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	100/514 (19%)
hspa12a	XP_002941887.2	HSPA12A_like_NBD	54..513	CDD:212685	97/490 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910