Protein Alignment Hsc70-1 and hspa1a

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_012823021.1
• Gene: hspa1a / 100488052
• XenbaseID: XB-GENE-5842877
• Length: 648
• Species: Xenopus tropicalis
• Alignment Length: 648
• Identity: 514/648 - (79%)
• Similarity: 581/648 - (89%)
• Gaps: 7/648 - (1%)

  Fly     1 MPKLPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNN 65
            |.|.|||||||||||||||||||||||||||||||||||||||||::||||||||||||||||.|
 Frog     1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65

  Fly    66 TIFDAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRET 130
            |:|||||||||||||..||||||||||.|..:.|:|:::||||||.|:||.|||||||||||:|.
 Frog    66 TVFDAKRLIGRRFDDPVVQSDMKHWPFTVINDGGRPKVQVEYKGEAKTFYAEEVSSMVLTKMKEI 130

  Fly   131 AEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNV 195
            :|||||.|:|:||:||||||||||||||||||.|:||||||||||||||||||||||:...||||
 Frog   131 SEAYLGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGGERNV 195

  Fly   196 LIFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRAL 260
            |||||||||||||:|||||||||||:|||||||||||||||:|||||.||:||||||:.:||||:
 Frog   196 LIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFVGEFKRKHKKDITENKRAI 260

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAK 325
            |||||||||||||||||||||||||||:||:|||||:|||||||||.||||||:|||.|||||||
 Frog   261 RRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSLTRARFEELNADLFRGTLEPVEKALRDAK 325

  Fly   326 MDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQD 390
            |||.||||||||||||||||:|:||||||||:|||||||||||||||||||||||.|||||.|||
 Frog   326 MDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILSGDKSENVQD 390

  Fly   391 LLLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNS 455
            |||||||||||||||||||||.||||||||||||||.||||:||||||||||||||||||:|||.
 Frog   391 LLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNL 455

  Fly   456 LGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVN 520
            ||||||:.||||||||||:|||||||||||:||:|::|||||||:|||||||||||||:|||||.
 Frog   456 LGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEEIERMVQ 520

  Fly   521 DAEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQ 585
            :|:.|:..||.||::|:|||.|||..|.::||::||.|..:.||.|::.|..:.:|.|:|||.||
 Frog   521 EADRYKAEDEVQREKISAKNSLESLAFNMKSTVEDEKLKDKISPEDKQKILDKCNEVISWLDRNQ 585

  Fly   586 LAERQEFEHKQQELERICSPIITRLYQGAGMAPPP-------TAGGSNPGATGGSGPTIEEVD 641
            :||::|:||:|:||:.:|:||||:||||||.|..|       ...|:..|..|.|||||||||
 Frog   586 MAEKEEYEHQQKELQNLCNPIITKLYQGAGGAGMPGGMPGGFPGAGAGAGGGGSSGPTIEEVD 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	512/646 (79%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	324/374 (87%)
hspa1a	XP_012823021.1	PTZ00009	1..612	CDD:240227	495/610 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		otm47512
Panther	1	1.100	-	-	O	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.030