Protein Alignment Hsc70-1 and hspa1b

DIOPT Version :10

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_002937685.2
• Gene: hspa1b / 100485441
• XenbaseID: XB-GENE-5915622
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 640
• Identity: 502/640 - (78%)
• Similarity: 575/640 - (89%)
• Gaps: 7/640 - (1%)

  Fly     6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIFDA 70
            |:||||||||||||||||||||||||||||||||||||||::|||||||||||||:||:||:|||
 Frog     7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPHNTVFDA 71

  Fly    71 KRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAYL 135
            ||||||::|:..||||||||||:|.::.|||::.||||||.|||.|||:||||||||:|||||||
 Frog    72 KRLIGRKYDEPVVQSDMKHWPFKVISDGGKPKVTVEYKGEGKSFSPEEISSMVLTKMKETAEAYL 136

  Fly   136 GGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIFDL 200
            |..||:||:||||.|||||||||||||.||||||||||||||||||||||||.|..|||:|||||
 Frog   137 GYKVTNAVITVPAXFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKSGRGERNILIFDL 201

  Fly   201 GGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRRLRT 265
            ||||||||:|||:|||||||||||||||||||||||:|||||:||:||||||:..||||||||||
 Frog   202 GGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISPNKRALRRLRT 266

  Fly   266 ACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMDKGQ 330
            |||||||||||||||||||||||||:|||||:||||||||..||||||:|||.||:||||:||.|
 Frog   267 ACERAKRTLSSSTQASIEIDSLFEGIDFYTSITRARFEELCADLFRGTLEPVEKAMRDAKLDKSQ 331

  Fly   331 IHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDLLLLD 395
            ||:||||||||||||||:||||||||||||||||||||||||||||||||.|||||.||||||||
 Frog   332 IHEIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLD 396

  Fly   396 VTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSLGKFE 460
            |.|||||:||||||||.||||||||||||||.||||:||||||||||:|||||||:|||.||||:
 Frog   397 VAPLSLGLETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFD 461

  Fly   461 LSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVNDAEAY 525
            |:.||||||||||:||||||||||||||:|::||:||:|:|||||||||||||:||||:.:|:.|
 Frog   462 LTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSSGKQNKITITNDKGRLSKEEIERMLQEADKY 526

  Fly   526 RQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQLAERQ 590
            :..|||||::|.|||.||||.|.::||::|.::..:.|..|:::|..:..|.|:||:.|||||::
 Frog   527 KADDEQQREKIAAKNSLESYAFNMKSTVEDNNIKDKISDNDKKSILDKCQEVISWLEQNQLAEKE 591

  Fly   591 EFEHKQQELERICSPIITRLYQGAGMAPPPTAGGSNPG----ATGGSGPTIEEVD 641
            |:.|||:|||::|:||||:|||| ||  |....|..||    |....||||||||
 Frog   592 EYTHKQKELEKLCNPIITKLYQG-GM--PGGMPGGMPGAGCTAEPKQGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	500/638 (78%)
hspa1b	XP_002937685.2	PTZ00009	2..643	CDD:240227	500/638 (78%)