Protein Alignment Hsc70-1 and hsp70.1

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001349288.1
• Gene: hsp70.1 / 100126123
• ZFINID: ZDB-GENE-990415-91
• Length: 643
• Species: Danio rerio
• Alignment Length: 642
• Identity: 500/642 - (77%)
• Similarity: 578/642 - (90%)
• Gaps: 4/642 - (0%)

  Fly     2 PKLPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNT 66
            ||..|:||||||||||||||||||||||||||||||||||||||::|||||||||||||||||||
Zfish     4 PKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNT 68

  Fly    67 IFDAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETA 131
            :|||||||||||||..||||||||.|:|.::.|||::.||:|||.|:|.|||:|||||.||:|.|
Zfish    69 VFDAKRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIA 133

  Fly   132 EAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVL 196
            |||||..||:||:||||||||||||||||||.||||||||||||||||||||||||..:||||||
Zfish   134 EAYLGQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVL 198

  Fly   197 IFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALR 261
            ||||||||||||:|||||||||||||||||||||||||||:|||||:||:||||||:.|||||||
Zfish   199 IFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALR 263

  Fly   262 RLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKM 326
            ||||||||||||||||:|||||||||:||:|||||:||||||||..||||||::||.|||:||||
Zfish   264 RLRTACERAKRTLSSSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALKDAKM 328

  Fly   327 DKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDL 391
            ||.||||||||||||||||:|:||||||||:|||||||||||||||||||||||.||.|..||||
Zfish   329 DKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQDL 393

  Fly   392 LLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSL 456
            |||||.||||||||||||||.||||||||||||||.||||:||||||||||||||||||:|||.|
Zfish   394 LLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLL 458

  Fly   457 GKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVND 521
            |||||:.||||||||||:||||||||||||||:|.:|||||:|:|||||||||||||:|||||.:
Zfish   459 GKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNKITITNDKGRLSKEEIERMVQE 523

  Fly   522 AEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQL 586
            |:.|:..|:.||::|:|||.||||.|.::::::|::|..:.|..|::.:.::.:|.::||:.|||
Zfish   524 ADKYKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRVIEKCNEAVSWLENNQL 588

  Fly   587 AERQEFEHKQQELERICSPIITRLYQGAGMAPPPTAGGSNPGATGGS--GPTIEEVD 641
            |:::|:||:.:|||::|:|:|::|||| || |....|....||:|.|  ||||||||
Zfish   589 ADKEEYEHQLKELEKVCNPVISKLYQG-GM-PAGGCGAQARGASGASAQGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	498/640 (78%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	323/374 (86%)
hsp70.1	NP_001349288.1	HSP70	5..643	CDD:331774	497/639 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575291
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		mtm6456
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.660